Viewing Study NCT00060788



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Last Modification Date: 2024-10-26 @ 9:08 AM
Study NCT ID: NCT00060788
Status: UNKNOWN
Last Update Posted: 2006-03-07
First Post: 2003-05-13

Brief Title: Antisocial Behavior Passing From Parent to Child to Grandchild
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Organization: Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD

Study Overview

Official Title: Intergenerational Transmission of Antisocial Behavior
Status: UNKNOWN
Status Verified Date: 2006-03
Last Known Status: RECRUITING
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Antisocial behavior often occurs in different generations within the same family However it is not known what factors contribute to this passing of antisocial behavior from parent to child to grandchild This study is part of a project evaluating antisocial behavior in families it focuses on the passage of such behavior from one generation to the next
Detailed Description: While it is well-known that antisocial behavior runs in families little is known about the specific mechanisms by which it is transmitted from one generation to the next This prospective study will examine biological influences on transgenerational continuity and change and how biology interacts with social factors in modulating the transmission of antisocial behavior The study is unique in that it includes both mothers and fathers focuses on early mechanisms and addresses female as well as male antisocial behavior

This study is part of the continuing Mauritius Child Health Project The project began by testing 1795 children age 3 years old on psychophysiological behavioral nutritional and cognitive measures Both male and female children were tested Their parents were also assessed for psychosocial influences One hundred children then participated in a nutritional exercise and educational enrichment intervention from ages 3 to 5 years old The intervention has been shown to increase physiological arousal and attention at age 11 years and to reduce conduct disorder at age 17 years

These 3-year-old children are now 30-year-old adults This study will retest these adults on psychophysiological psychosocial cognitive behavioral parenting and antisocial behavior measures Their previously untested spouses will also be assessed Finally many of these adults now have 3-year-old children of their own these children will be evaluated as well Measures of life stress daily hassles family conflict mental illness and criminal behavior will be assessed Data from the enrichment cohort will be evaluated to determine if the intervention disrupted the intergenerational transmission of antisocial behavior from the second to third generations

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None