Ignite Creation Date:
2024-05-05 @ 11:00 PM
Last Modification Date:
2024-10-26 @ 10:27 AM
Study NCT ID:
NCT01239225
Status:
COMPLETED
Last Update Posted:
2010-11-11
First Post:
2010-11-07
Brief Title:
Prevalence of Abdominal Aortic Aneurysm in Patients Undergoing Coronary Angiography
Sponsor:
Meir Medical Center
Organization:
Meir Medical Center
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2010-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Abdominal aortic aneurysms AAA are localized blood-filled dilations balloon-like bulges of the aorta Approximately 90 of abdominal aortic aneurysms occur infrarenally 1 It is most commonly asymptomatic and can be detected randomly during screening Its prevalence rate in men aged 65 years and more is 5 - 8 3
The risk factors for the occurrence of AAA are male gender advanced age history of atherosclerosis cigarette smoking and 1st degree family history 4
The prevalence rate is higher in patients with history of atherosclerosis of peripheral blood vessels and coronary arteries 5 - 7 As the size of an aneurysm increases there is an increased risk of rupture which can result in severe hemorrhage and death The death rate due to rupture in the elderly population is 90 3 8 Elective surgical repair of the abdominal aortic aneurysm is associated with a death rate of 8 9 Therefore the importance of the screening of populations at elevated risk is obvious 5 - 7 10 -14 Among imaging techniques ultrasonographic screening for abdominal aortic aneurysm is technically simple accurate and devoid of ionizing radiation Ultrasonographic diagnosis of AAA is associated with a major reduction in the incidence of abdominal aortic aneurysm-related mortality 15 - 19 The sensitivity of ultrasonographic screening for abdominal aortic aneurysm is about 100 19 The most common clinical indications for ultrasonographic screening for abdominal aortic aneurysm are a palpable abdominal mass hemodynamic impairment of aortic system in lower extremities pain in the chest lower back or scrotum and abdominal bruits
Ultrasonography is used to screen for aneurysms when the outer aortic diameter is more than 3 cm normal diameter of the aorta is around 2 cm 20 There is disagreement regarding the follow-up of patients after detection of abdominal aortic aneurysm in diameter of 26 cm - 29 cm 22 Random detection of abdominal aortic aneurysm where the aortic diameter is 26 cm in men aged 65 years and more have been associated with no risk for its future significant development 21 Ultrasonographic evaluation of abdominal aorta is a challenge for clinicians because of the need for the accurate detection of aortic diameter 20
The risk factors for the occurrence of AAA are male gender advanced age history of atherosclerosis cigarette smoking and 1st degree family history 4
The prevalence rate is higher in patients with history of atherosclerosis of peripheral blood vessels and coronary arteries 5 - 7 As the size of an aneurysm increases there is an increased risk of rupture which can result in severe hemorrhage and death The death rate due to rupture in the elderly population is 90 3 8 Elective surgical repair of the abdominal aortic aneurysm is associated with a death rate of 8 9 Therefore the importance of the screening of populations at elevated risk is obvious 5 - 7 10 -14 Among imaging techniques ultrasonographic screening for abdominal aortic aneurysm is technically simple accurate and devoid of ionizing radiation Ultrasonographic diagnosis of AAA is associated with a major reduction in the incidence of abdominal aortic aneurysm-related mortality 15 - 19 The sensitivity of ultrasonographic screening for abdominal aortic aneurysm is about 100 19 The most common clinical indications for ultrasonographic screening for abdominal aortic aneurysm are a palpable abdominal mass hemodynamic impairment of aortic system in lower extremities pain in the chest lower back or scrotum and abdominal bruits
Ultrasonography is used to screen for aneurysms when the outer aortic diameter is more than 3 cm normal diameter of the aorta is around 2 cm 20 There is disagreement regarding the follow-up of patients after detection of abdominal aortic aneurysm in diameter of 26 cm - 29 cm 22 Random detection of abdominal aortic aneurysm where the aortic diameter is 26 cm in men aged 65 years and more have been associated with no risk for its future significant development 21 Ultrasonographic evaluation of abdominal aorta is a challenge for clinicians because of the need for the accurate detection of aortic diameter 20
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None