Ignite Creation Date:
2024-05-05 @ 10:59 PM
Last Modification Date:
2024-10-26 @ 10:26 AM
Study NCT ID:
NCT01226199
Status:
UNKNOWN
Last Update Posted:
2011-06-08
First Post:
2010-10-21
Brief Title:
The Expression of TLR2 and TLR4 in the Lung of Chronic Obstructive Pulmonary Disease COPD Patients
Sponsor:
Seoul National University Bundang Hospital
Organization:
Seoul National University Bundang Hospital
Study Overview
Official Title:
The Expression of TLR2 and TLR4 in the Lung of COPD Patients
Status:
UNKNOWN
Status Verified Date:
2011-06
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Smoking is the most important risk factor of COPD but only a fourth of smokers had COPD in their life There are also healthy smokers without evidence of COPD Investigators hypothesize that innate immunity may affect this difference between COPD patients and healthy smokers because TLR4 is the receptor of LPS which is the one of important substance in cigarette Investigators will measure TLR2 and TLR4 expression in lung tissue of patients whose lung will be resected Investigators will compare the level of expression between COPD patients and healthy smokers
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None