Ignite Creation Date:
2024-05-05 @ 10:51 PM
Last Modification Date:
2024-10-26 @ 10:25 AM
Study NCT ID:
NCT01204645
Status:
UNKNOWN
Last Update Posted:
2017-06-15
First Post:
2010-09-16
Brief Title:
Karolinska Cardiorenal Theme-centre and StockholmHeartbank
Sponsor:
Danderyd Hospital
Organization:
Danderyd Hospital
Study Overview
Official Title:
Stockholmheartbank and Karolinska Cardiorenal Theme-centre From Genome to Clinical Practice in Patients With Acute Coronary Syndrome and Impaired Kidney Function
Status:
UNKNOWN
Status Verified Date:
2017-06
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
KKT
Brief Summary:
Chronic kidney disease CKD affects 10-18 of the adult population and is becoming recognized as one of the most serious disorders causing increased risk for cardiovascular disease and death In patients with ischemic heart disease 26 have increased creatinine which rises to 40 if patients also have diabetes mellitus Risk increases as renal function diminishes and just slowing the rate of decline in renal function would have a tremendous impact on health and morbidity This association is commonly termed the Cardiorenal Syndrome though it is caused by a much more complex interplay between major pathogenetic pathways such as glucose metabolism and diabetes systemic and tissue inflammation tissue metabolism coagulation mineral metabolism sympathetic activation renin-angiotensin-aldosterone system activation endothelial dysfunction lipid metabolism fetal programming etc
Karolinska Institutet recently merged basic and clinical researchers in all these fields creating a Karolinska Kardiorenal Theme Centre ultimately aiming to explore the syndrome and provide improved care for the individual patient
The investigators road to success
Creating a Biobank blood DNA plasma from the majority of all hosptalized patients with ACS in Stockholm county - Stockholmheartbank
This Theme Center include all teaching hospitals associated with Karolinska Institutet Danderyd University Hospital Karolinska University Hospital and Södersjukhuset University Hospital Together theses hospitals serve as emergency hospitals for 19 million people The investigators are aiming at creating a biobank from all patients admitted for an acute coronary event about 2300yr which is a unique asset for molecular and genetic research as well as observational and intervention studies
The investigators have access to the National registry with 100 coverage that contains data on all patients admitted to Stockholms coronary care units since 1995
To ensure translation in to clinical practice most of the researchers are also MDs and several are clinically active
The clinical network facilitates the development of novel therapies and translational research
Steering groups for Education and a Clinical Practice implementation program
Karolinska Institutet recently merged basic and clinical researchers in all these fields creating a Karolinska Kardiorenal Theme Centre ultimately aiming to explore the syndrome and provide improved care for the individual patient
The investigators road to success
Creating a Biobank blood DNA plasma from the majority of all hosptalized patients with ACS in Stockholm county - Stockholmheartbank
This Theme Center include all teaching hospitals associated with Karolinska Institutet Danderyd University Hospital Karolinska University Hospital and Södersjukhuset University Hospital Together theses hospitals serve as emergency hospitals for 19 million people The investigators are aiming at creating a biobank from all patients admitted for an acute coronary event about 2300yr which is a unique asset for molecular and genetic research as well as observational and intervention studies
The investigators have access to the National registry with 100 coverage that contains data on all patients admitted to Stockholms coronary care units since 1995
To ensure translation in to clinical practice most of the researchers are also MDs and several are clinically active
The clinical network facilitates the development of novel therapies and translational research
Steering groups for Education and a Clinical Practice implementation program
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None