Ignite Creation Date:
2024-05-05 @ 10:48 PM
Last Modification Date:
2024-10-26 @ 10:25 AM
Study NCT ID:
NCT01199991
Status:
TERMINATED
Last Update Posted:
2019-03-15
First Post:
2010-09-07
Brief Title:
Comparison of Xtreme CT and DXA Bone Densitometry
Sponsor:
Massachusetts General Hospital
Organization:
Massachusetts General Hospital
Study Overview
Official Title:
Comparison of Xtreme CT and DXA Bone Densitometry
Status:
TERMINATED
Status Verified Date:
2019-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Limited funding change in research priorities
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Dual-energy x-ray absorptiometry DXA is currently the most widely used tool for determining bone density However most experts consider DXA an imperfect and intermediate technology DXA is subject to artifact from arthritis and body composition and also cannot account for geometric or material properties of bone which are also important components of bone strength
Xtreme CT high-resolution peripheral quantitative computed tomography HR-pQCT is a new technology with dramatically improved spatial resolution It is able to define bones cortical and trabecular surfaces in a three-dimensional manner and therefore provides information on bone microarchitecture as well as bone density As such it may provide new information about characteristics of bone strength
The purpose of this study is to compare Xtreme CT to DXA measurements of bone density and also to generate a normative database of healthy young adults This cross-sectional study involves a single visit where both Xtreme CT and DXA measurements will be obtained for a single time-point This normative database will allow us to generate clinically relevant comparisons between the two imaging technologies
Xtreme CT high-resolution peripheral quantitative computed tomography HR-pQCT is a new technology with dramatically improved spatial resolution It is able to define bones cortical and trabecular surfaces in a three-dimensional manner and therefore provides information on bone microarchitecture as well as bone density As such it may provide new information about characteristics of bone strength
The purpose of this study is to compare Xtreme CT to DXA measurements of bone density and also to generate a normative database of healthy young adults This cross-sectional study involves a single visit where both Xtreme CT and DXA measurements will be obtained for a single time-point This normative database will allow us to generate clinically relevant comparisons between the two imaging technologies
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None