Ignite Creation Date:
2024-05-05 @ 10:47 PM
Last Modification Date:
2024-10-26 @ 10:23 AM
Study NCT ID:
NCT01183442
Status:
TERMINATED
Last Update Posted:
2015-04-17
First Post:
2010-08-16
Brief Title:
Vitamin D Supplementation in CAD and Postchallenge Hyperglycemia
Sponsor:
Medical University of Graz
Organization:
Medical University of Graz
Study Overview
Official Title:
Effects of Vitamin D Supplementation in Coronary Artery Disease Patients With Postchallenge Hyperglycemia and Vitamin D Deficiency on Endothelial Function and Insulin Sensitivity
Status:
TERMINATED
Status Verified Date:
2015-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
unable to recruit
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The main aim of the investigation is to clarify whether vitamin D supplementation in coronary artery disease patients with vitamin D deficiency and postchallenge hyperglycemia has an impact on endothelial dysfunction and parameters of insulin sensitivity and beta-cell function
Detailed Description:
An improvement of endothelial dysfunction as a cardiovascular surrogate parameter could be translated in a reduced risk for future cardiovascular events which is of major interest since patients with postchallenge hyperglycemia face a significantly higher cardiovascular risk than patients with normal glucose tolerance Furthermore an improvement in insulin sensitivity andor beta-cell function would identify vitamin D as an important strategy for the prevention of type 2 diabetes In consideration of the rapidly increasing prevalence of diabetes and the failure of current prevention strategies this could be an important safe and cheap way to support ongoing lifestyle modifying programs Our study of course investigates surrogate cardiovascular and insulin sensitivity parameters Assuming a beneficial effect of vitamin D in our study this concept would have to be proven in further large outcome as well as diabetes prevention trials
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None