Ignite Creation Date:
2024-05-05 @ 10:46 PM
Last Modification Date:
2024-10-26 @ 10:24 AM
Study NCT ID:
NCT01189578
Status:
COMPLETED
Last Update Posted:
2012-10-29
First Post:
2010-08-25
Brief Title:
Brain Imaging of Cocaine Craving in Recreational Cocaine Users
Sponsor:
James J Prisciandaro
Organization:
Medical University of South Carolina
Study Overview
Official Title:
Neural Correlates of Craving and Impulsivity in Recreational Cocaine Users
Status:
COMPLETED
Status Verified Date:
2012-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to compare individuals with cocaine dependence to recreational users of cocaine in terms of their brain reactivity to cocaine cues in hopes that this comparison may help us better understand the transition from recreational to compulsive cocaine use
Detailed Description:
Chronic cocaine exposure is associated with an intensified and broadened pattern of neural reactivity to cocaine and cocaine cues prolonged use is also associated with prefrontal abnormalities during response inhibition Limited research suggests that recreational cocaine use has similar but attenuated effects on neural functioning Unfortunately very little research has directly compared cocaine dependent individuals and recreational cocaine users in terms of their neural reactivity to cocaine cues and response inhibition Such comparisons could help to elucidate the pathological neuroplasticity associated with the transition from cocaine use to dependence The proposed study will assess neural reactivity to cocaine cues and response inhibition in recreational cocaine users using fMRI These data will be compared to data from the baseline visit of an ongoing IRB approved investigation NCT00759473 in cocaine dependent individuals that is using the same experimental procedures as the proposed study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01DA023188 | NIH | None | httpsreporternihgovquickSearchR01DA023188 |