Ignite Creation Date:
2025-12-25 @ 12:37 AM
Ignite Modification Date:
2025-12-25 @ 10:47 PM
Study NCT ID:
NCT07174167
Status:
COMPLETED
Last Update Posted:
2025-11-28
First Post:
2025-09-02
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Genicular Nerve Block in Chronic Knee Osteoarthritis
Sponsor:
Haydarpasa Numune Training and Research Hospital
Organization:
Study Overview
Official Title:
Effectiveness of Genicular Nerve Block on Pain and Disability in Chronic Knee Osteoarthritis: A Randomized Controlled Trial
Status:
COMPLETED
Status Verified Date:
2025-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
GNB-KOA-RCT
Brief Summary:
The goal of this clinical trial is to evaluate whether genicular nerve block (GNB) is effective in reducing pain in patients with knee osteoarthritis. It will also assess the comparative efficacy of different injection protocols.
The main questions it aims to answer are:
Does genicular nerve block with corticosteroid and local anesthetic provide superior pain relief compared with local anesthetic alone or placebo?
Are there differences in clinical outcomes between the three treatment groups?
Researchers will compare three groups:
GNB with corticosteroid plus local anesthetic
GNB with local anesthetic alone
Sham procedure with saline (placebo control)
Participants will:
Receive the assigned injection protocol in accordance with their group
Be evaluated at baseline and scheduled follow-up visits for pain intensity and functional status
Report their pain scores and functional limitations using standardized assessment tools
The main questions it aims to answer are:
Does genicular nerve block with corticosteroid and local anesthetic provide superior pain relief compared with local anesthetic alone or placebo?
Are there differences in clinical outcomes between the three treatment groups?
Researchers will compare three groups:
GNB with corticosteroid plus local anesthetic
GNB with local anesthetic alone
Sham procedure with saline (placebo control)
Participants will:
Receive the assigned injection protocol in accordance with their group
Be evaluated at baseline and scheduled follow-up visits for pain intensity and functional status
Report their pain scores and functional limitations using standardized assessment tools
Detailed Description:
None
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?: