Ignite Creation Date:
2024-05-05 @ 10:41 PM
Last Modification Date:
2024-10-26 @ 10:22 AM
Study NCT ID:
NCT01167842
Status:
COMPLETED
Last Update Posted:
2022-02-03
First Post:
2010-07-20
Brief Title:
Analysis of Tumors From Patients With Inherited Cancers Having Had Two Surgeries Primary Recurrent or 2 Separate Types of Cancer
Sponsor:
University of Washington
Organization:
University of Washington
Study Overview
Official Title:
Analysis of Inherited Cancers
Status:
COMPLETED
Status Verified Date:
2022-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will analyze tumor tissue from patients with known genetic mutations BRCA1 BRCA2 CHK2 etc who have tumor tissue available from two surgeries either primaryrecurrent or two different anatomical sites
Detailed Description:
This study will recruit individuals with known BRCA1 and BRCA2 mutations or mutations in similar cancer causing genes such as CHK2 or PALB2 who have had a cancer removed by surgery or biopsied two or more times with available pathological blocks We wish to enroll individuals who have had more than one surgery or biopsy for cancer allowing us to obtain tumor blocks from more than one time point Such patients would include those with one cancer which has recurred or more than one separate cancer We will conduct a brief interview with the subject to obtain personal information about medical and treatment history In addition we will collect clinical information from their treating physicians to correlate molecular findings with clinical responses to treatment and survival and recurrence data We will collect background clinical information and family history information and a copy of the genetic test results documenting their cancer causing mutation We will recruit only patients with known BRCA1 or BRCA2 mutations or known mutations in other cancer causing genes such as CHK2 or PALB2 and will not perform genetic testing on non-tumor tissue for any new information on genetic susceptibility in patient samples Enrolled subjects will donate a blood sample that will be obtained locally and shipped to the research laboratory and this cost will be entirely covered by the research group
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| P50CA083636 | NIH | None | httpsreporternihgovquickSearchP50CA083636 |