Ignite Creation Date:
2024-05-05 @ 11:30 AM
Last Modification Date:
2024-10-26 @ 9:09 AM
Study NCT ID:
NCT00069134
Status:
COMPLETED
Last Update Posted:
2017-08-01
First Post:
2003-09-15
Brief Title:
Study of Antioxidants and Oxidants in Malnourished Children
Sponsor:
Baylor College of Medicine
Organization:
Baylor College of Medicine
Study Overview
Official Title:
Glutathione Homeostasis and Oxidant Damage in Kwashiorkor
Status:
COMPLETED
Status Verified Date:
2017-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
It is believed that the organs of severely malnourished children malfunction because harmful compounds called oxidants injure the tissues in these organs In a healthy person oxidants are made harmless because another compound called glutathione neutralizes them Glutathione is made from three amino acids that we get from the protein we eat in our food We found that malnourished children were not making enough glutathione because they lacked one of these amino acids called cysteine In this study we determine why malnourished children do not have sufficient cysteine and we will feed malnourished children a whey-based diet which is rich in cysteine during their treatment to determine whether they will make more glutathione This in turn may make their organs recover faster These findings will let us know whether malnourished children can recover faster if they are given more cysteine during the early phase of treatment
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01DK056689 | NIH | None | httpsreporternihgovquickSearchR01DK056689 |