Ignite Creation Date:
2024-05-05 @ 10:31 PM
Last Modification Date:
2024-10-26 @ 10:20 AM
Study NCT ID:
NCT01128465
Status:
COMPLETED
Last Update Posted:
2011-03-17
First Post:
2010-02-22
Brief Title:
Pharmacokinetic and -Dynamic of Propofol During Awake Craniotomy
Sponsor:
University Hospital Bonn
Organization:
University Hospital Bonn
Study Overview
Official Title:
Investigation on the Pharmacokinetic and -Dynamic of Propofol During Awake Craniotomy
Status:
COMPLETED
Status Verified Date:
2011-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Certain kind of neurosurgical procedures require intraoperative alertness of the patient for example to perform speech tests during brain tumor resection With respect to anaesthesia it is therefore required that the patient is asleep during the beginning and the end of the procedure however fully awake in between To do so the anaesthetic propofol is used and an accurate knowledge of its pharmacokinetic and -dynamic pkpd parameters is required to optimally control anaesthesia However diverse pkpd-parameter sets have been described in the literature
The aim of the study is to investigate whether the pkpd model proposed by Marsh et al or by Schnider et al more accurately describe the pkpd of propofol during awake craniotomy
The aim of the study is to investigate whether the pkpd model proposed by Marsh et al or by Schnider et al more accurately describe the pkpd of propofol during awake craniotomy
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None