Ignite Creation Date:
2024-05-05 @ 10:27 PM
Last Modification Date:
2024-10-26 @ 10:18 AM
Study NCT ID:
NCT01100762
Status:
COMPLETED
Last Update Posted:
2019-10-30
First Post:
2010-03-19
Brief Title:
Transcranial Direct Current Stimulation tDCS and Parkinsons Disease
Sponsor:
University of Maryland Baltimore
Organization:
University of Maryland Baltimore
Study Overview
Official Title:
Can Transcranial Direct Current Stimulation tDCSModulate Protective Stepping and Gait Performance of People With Parkinsons Disease
Status:
COMPLETED
Status Verified Date:
2019-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The use of low level electrical stimulation when applied over the head also called transcranial direct current stimulation tDCS is being tested by several groups of researchers to see if tDCS can improve movements of persons with damage to the brain The safety and potential benefits of tDCS to children or adults patients who are paralyzed because of brain damage are reported in the medical literature In addition some patients with Parkinsons disease PD experience improvement in memory and report better use of the hand after tDCS The treatment requires putting electrodes pads over the head and sending very small amount of electrical current that the patient may feel as little tingling Application of tDCS takes 20 min In this study we wish to test if tDCS application can improve stepping and walking ability of subjects with PD and if the improvement is the same as when walking on treadmill We plan to test the subjects ability to step when pulled by a laboratory testing system and also test hisher walking ability There will be 3 sessions 7 days apart In the first session the subject will be tested then treated for 20 min with tDCS and then tested again In the second session the subject will be tested then walk on a treadmill for 20 min then tested again In the third session the subject will be tested then walk on the treadmill for 20 min while receiving also tDCS and tested one last time at the end of the session Each session will take between 2 and 3 hours
Detailed Description:
Recent advances in non-invasive electrical stimulation technology including transcranial direct current stimulation tDCS have provided novel and low risk options to rehabilitate the impaired ability of the central nervous system CNS to process sensorimotor information Furthermore tDCS appears to enhance CNS connectivity and there is preliminary evidence indicating that patients with Parkinsons Disease PD may experience improvement in working memory the Unified Parkinsons Disease Rating Scale simple reaction time and the Purdue Pegboard test tDCS is inexpensive portable and available for repeated home use It may provide long-lasting enhancement of cortical activity in part because tDCS is easy to administer frequently and to combine it with other rehabilitation approaches including posture and gait training However to date no study has examined quantitatively the effects of tDCS on posture control and walking ability in patients with PD As a first step we plan to identify the immediate effects of tDCS as well as the added value of tDCS to treadmill exercise training to improve posture and gait of individuals with PD
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None