Viewing Study NCT01105845



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Last Modification Date: 2024-10-26 @ 10:18 AM
Study NCT ID: NCT01105845
Status: TERMINATED
Last Update Posted: 2019-11-22
First Post: 2010-04-16

Brief Title: Genetics of Motor Learning
Sponsor: National Institute of Neurological Disorders and Stroke NINDS
Organization: National Institutes of Health Clinical Center CC

Study Overview

Official Title: Genetics of Motor Learning
Status: TERMINATED
Status Verified Date: 2015-12-21
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Background

- New studies in human genetics have revealed information about genetic connections to memory and motor behavior Researchers are interested in investigating the role of genetics in motor learning in conjunction with related studies taking place in the Human Motor Control Section of the National Institute of Neurological Diseases and Stroke NINDS Participants in motor learning studies conducted at NINDS will be asked to provide blood samples for further evaluation

Objectives

- To create a repository of blood samples from patients and healthy subjects who are participating in NINDS motor learning studies

Eligibility

- Individuals between 18 and 100 years of age who are or will be participating in motor learning research studies at the National Institutes of Health

Design

Blood draws for genetic testing will usually be done on the same day as the motor learning study Participants will provide one blood sample for research
No treatment will be provided under this study
Detailed Description: OBJECTIVETAB

The objective of this study is to create a bio-repository of blood samples from patients and healthy subjects who are participating in NINDS motor learning studies Blood will be analyzed for BDNF and samples stored for future genetic studies A variety of genes that may affect motor learning are being increasingly identified and variations among these genes referred to as polymorphisms may help explain individual differences

STUDY POPULATION TAB

We will enroll up to five hundred healthy volunteers and five hundred volunteers with movement difficulties who are between the ages of 18 and 100 and who are already participating or will be participating in other protocols dealing with motor learning research studies at the National Institutes of Health NIH

DESIGNTAB

This is an observational and repository protocol that involves a single blood sample for genetic analysis This will allow the genetic characterization of subjects participating in motor learning protocols to be analyzed and tested for the role of genetics in motor learning results

OUTCOME MEASURE

We will compare genetic variations with the different behavioral electrophysiologic imaging or other outcomes acquired in the associated motor learning studies Thus we will determine whether specific polymorphisms are associated with different measures of motor learning

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None
Secondary IDs
Secondary ID Type Domain Link
10-N-0092 None None None