Ignite Creation Date:
2024-05-05 @ 10:23 PM
Last Modification Date:
2024-10-26 @ 10:17 AM
Study NCT ID:
NCT01092598
Status:
COMPLETED
Last Update Posted:
2015-05-27
First Post:
2010-03-23
Brief Title:
Factors Association With Poor Physical Function in Older Adults With Schizophrenia
Sponsor:
University of California San Francisco
Organization:
University of California San Francisco
Study Overview
Official Title:
The Impact of Neurocognition and Symptomatology on Physical Function Among Older Adults With Schizophrenia
Status:
COMPLETED
Status Verified Date:
2015-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Older adults with schizophrenia are a growing segment of the population yet their physical health status is poor In order to design effective interventions the contributing factors must be understood Current data suggest the side effects of psychiatric medications sociodemographic factors and health care disparities are a few of the reasons for the poor physical health There are only limited data on the impact of psychiatric symptomatology and neurocognition on the physical health of this population These limited data indicate that worse symptomatology and poorer neurocognition may negatively impact physical functioning a critical component to optimal physical health The purpose of this pilot study is to begin to fill this knowledge gap by 1 examining the relationship between neurocognitive function and physical function and 2 Examining the relationship between schizophrenia symptoms and physical function 3 Examining the relationship between serum Brain Derived Neurotrophic Factor BDNF and physical function Using a descriptive correlational design 50 older adults 55 with schizophrenia or schizoaffective disorder will be assessed Bivariate associations will be used to examine the relationship between key variables including schizophrenia symptoms as measured by the Positive and Negative Syndrome Scale PANSS neurocognitive function as measured with the MATRICS Consensus Cognitive Battery MCCB Physical Function as measured objectively by the Timed Get Up and Go TGUG test and subjectively with the physical component summary subscale of the 12-item short form health survey SF-12 and serum BDNF These pilot data will lay the foundation for a future health promoting intervention
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None