Ignite Creation Date:
2024-05-05 @ 10:00 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00004274
Status:
COMPLETED
Last Update Posted:
2005-06-24
First Post:
1999-10-18
Brief Title:
Effect of Estrogen on Mental and Social Functioning in Girls With Turners Syndrome
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
Office of Rare Diseases ORD
Study Overview
Official Title:
Controlled Study of Estrogen Effects on Cognitive and Social Function in Girls With Turners Syndrome
Status:
COMPLETED
Status Verified Date:
2003-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
RATIONALE Turners syndrome is a disease in which females are missing all or part of one X chromosome and do not produce estrogen Giving estrogen is standard treatment for girls who have Turners syndrome Estrogen may be effective treatment for mental and social functioning problems experienced by girls with Turners syndrome
PURPOSE Clinical trial to study the effectiveness of long term estrogen therapy on mental and social functioning in girls who have Turners syndrome
PURPOSE Clinical trial to study the effectiveness of long term estrogen therapy on mental and social functioning in girls who have Turners syndrome
Detailed Description:
PROTOCOL OUTLINE Participants are evaluated for cognitive and social function at entry and 4 years following entry Assessments include the Wechsler Intelligence Scale for Children-Revised a child behavior checklist the Childrens Self-Concept Scale and visual-spatial visual-motor attention memory language and facial recognition tasks
Patients and parents undergo X-chromosome analysis brain magnetic imaging is optional
Controls are matched using school selection and telephone interviews
A study duration of 12 years is estimated
Patients and parents undergo X-chromosome analysis brain magnetic imaging is optional
Controls are matched using school selection and telephone interviews
A study duration of 12 years is estimated
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| TJU-11680 | None | None | None |