Ignite Creation Date:
2024-05-05 @ 10:18 PM
Last Modification Date:
2024-10-26 @ 10:16 AM
Study NCT ID:
NCT01071759
Status:
UNKNOWN
Last Update Posted:
2010-02-19
First Post:
2010-02-18
Brief Title:
Effects of Dietary HemeNon-heme Iron and Helicobacter Pylori Hp Infection on Maternal Iron-deficiency Anemia and Fetal Growth Outcomes
Sponsor:
E-DA Hospital
Organization:
E-DA Hospital
Study Overview
Official Title:
Effects of Dietary HemeNon-heme Iron and Hp Infection on Maternal Iron-deficiency Anemia and Fetal Growth Outcomes - a Perinatal Longitudinal Study
Status:
UNKNOWN
Status Verified Date:
2010-02
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Iron deficiency is considered one of the main nutritional deficiency disorders despite the apparent availability of a high-quality diet even in developed countries and Iron deficiency anemia IDA is the most common form of anemia in the world IDA during pregnancy has been associated with adverse health consequences for both the mother and her developing fetus Helicobacter pylori Hp may be the most common bacterial infection worldwide infecting almost half of people in developed countries and 80 of people in developing countries The available data on the prevalence of Hp infection in Taiwan population was 544 We all know that infection with Hp is strongly associated with peptic ulcer and gastric cancer but recent evidence suggests that Hp is associated with iron deficiency and anemia although the mechanisms remain unclear Till now only few previous studies specifically have addressed a potential role of Hp infection on anemia or iron deficiency during pregnancy Our previous Research showed between the Hp infection and Hp infection - gravidas the associations between the Hp infection and iron deficiency were stronger although not statistically significant This might be due to that we needed more cases and evidences to prove the relationship between maternal Hp infection and serum iron ferritin and hemoglobin levels or we should further consider the interactions of the particular customs or diet preference of the Taiwanese gravidas This longitudinal study will recruit 140 women from the antenatal care clinics of E-Da Hospital to examine the association between Hp infection and maternal IDA The standardized interviews of mothers anthropometric data socioeconomic status medical history obstetric history alcohol consumption during pregnancy and history and duration of iron supplementation during pregnancy will be conducted Hp infection status will be determined by the urea breath test and IgG enzyme immunoassay and the measurement of hemoglobin iron and ferritin levels will be obtained 5 times at various antepartum and postpartum points of time during pregnancy routine prenatal visits of 1st 2nd and 3rd trimester puerperium and 2 weeks after delivery We hope that we could investigate the possible role of Hp infection in iron deficiency and iron-deficiency anemia during pregnancy in Taiwan and that early detection and treatment of anemia may reduce the risk of blood transfusion and perinatal and maternal mortality
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| EMRP-097-123 | OTHER | E-DA Hospital | None |