Ignite Creation Date:
2025-12-24 @ 11:49 PM
Ignite Modification Date:
2025-12-25 @ 9:43 PM
Study NCT ID:
NCT06372951
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-04-18
First Post:
2023-11-29
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Lung Ultrasound in Neonatal Intensive Care Units
Sponsor:
Assiut University
Organization:
Study Overview
Official Title:
Role of Lung Ultrasound in Assessment of Neonatal Respiratory Distress
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Identification of lung diseases causing neonatal respiratory distress by lung ultrasound as a tool that can replace x-ray .
Detailed Description:
* Lung disease is the most common cause of neonatal respiratory distress.
* It can result in respiratory failure and death in severe cases.
* The mortality rate is approximately 11%:32%.
* Identification of the etiology of lung disease is important for neonatologists.
* Traditionally, chest X-ray has been considered as the most valuable imaging modality for the diagnosis of lung diseases, but it unavoidably causes radiation damage to the patient.
* Neonates are susceptible to radiation because they have rapidly dividing cells that cannot repair mutated DNA.
* The risk of cancer induction in infants receiving a single small dose of radiation is 2-3 times higher than the average population and 6-9 times higher than the risk from an exposure of a 60-year-old patient.
* New imaging modalities have been introduced in clinical practice in recent years such as lung ultrasound.
* One of the most common causes of neonatal respiratory distress that can be diagnosed by ultrasound is :Respiratory Distress Syndrome:
* Respiratory distress syndrome.. is a major cause of neonatal mortality.
* It mainly occur in preterm infants due to structural and functional lung immaturity.
* Pulmonary surfactant insufficiency is an important pathogenesis in respiratory distress syndrome.
* The ultrasonic features of respiratory distress syndrome are: Compact B-Lines, white lung appearance, abnormality in pleural line (thick and irregular),lung consolidation.
* Lung ultrasound has the advantages of :
* Non-ionizing.
* Easy to operate.
* Low coast.
* Portable for bedside use.
* The imaging is performed in real-time.
* Thus making it as a potential tool to be used in neonatal intensive care units.
* It can result in respiratory failure and death in severe cases.
* The mortality rate is approximately 11%:32%.
* Identification of the etiology of lung disease is important for neonatologists.
* Traditionally, chest X-ray has been considered as the most valuable imaging modality for the diagnosis of lung diseases, but it unavoidably causes radiation damage to the patient.
* Neonates are susceptible to radiation because they have rapidly dividing cells that cannot repair mutated DNA.
* The risk of cancer induction in infants receiving a single small dose of radiation is 2-3 times higher than the average population and 6-9 times higher than the risk from an exposure of a 60-year-old patient.
* New imaging modalities have been introduced in clinical practice in recent years such as lung ultrasound.
* One of the most common causes of neonatal respiratory distress that can be diagnosed by ultrasound is :Respiratory Distress Syndrome:
* Respiratory distress syndrome.. is a major cause of neonatal mortality.
* It mainly occur in preterm infants due to structural and functional lung immaturity.
* Pulmonary surfactant insufficiency is an important pathogenesis in respiratory distress syndrome.
* The ultrasonic features of respiratory distress syndrome are: Compact B-Lines, white lung appearance, abnormality in pleural line (thick and irregular),lung consolidation.
* Lung ultrasound has the advantages of :
* Non-ionizing.
* Easy to operate.
* Low coast.
* Portable for bedside use.
* The imaging is performed in real-time.
* Thus making it as a potential tool to be used in neonatal intensive care units.
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: