Ignite Creation Date:
2024-05-05 @ 10:03 PM
Last Modification Date:
2024-10-26 @ 10:13 AM
Study NCT ID:
NCT01016665
Status:
COMPLETED
Last Update Posted:
2009-11-19
First Post:
2009-11-17
Brief Title:
Anastrozole Reduced Proliferation and Progesterone Receptor Indexes in Short Term Hormone Therapy
Sponsor:
Federal University of São Paulo
Organization:
Federal University of São Paulo
Study Overview
Official Title:
Anastrozole Reduced Proliferation and Progesterone Receptor Indexes in Short Term Hormone Therapy A Prospective Placebo Double Blind Study
Status:
COMPLETED
Status Verified Date:
2009-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background Identification of new biomarkers with potential predictive and prognostic role has contributed unequivocally to breast cancer treatment
Although traditionally endocrine therapy is based on hormonal receptors status estrogen - ER and progesterone- PR some patients become hormone resistant In order to identify a possible profile associated to hormonal resistance some biomarkers have been assessed after short period primary hormone therapy HT
Objectives To compare the expression of Ki-67 Bcl2 Bax Bak ER and e PR in postmenopausal women with ER positive invasive ductal carcinomas IDC prior and after tamoxifen and anastrozole in short term hormone therapy
Although traditionally endocrine therapy is based on hormonal receptors status estrogen - ER and progesterone- PR some patients become hormone resistant In order to identify a possible profile associated to hormonal resistance some biomarkers have been assessed after short period primary hormone therapy HT
Objectives To compare the expression of Ki-67 Bcl2 Bax Bak ER and e PR in postmenopausal women with ER positive invasive ductal carcinomas IDC prior and after tamoxifen and anastrozole in short term hormone therapy
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None