Ignite Creation Date:
2024-05-05 @ 10:02 PM
Last Modification Date:
2024-10-26 @ 10:12 AM
Study NCT ID:
NCT01012180
Status:
COMPLETED
Last Update Posted:
2018-04-05
First Post:
2009-11-10
Brief Title:
Parents With Bipolar Disorder Relationship of Adaptation to Own Illness With Risk Perception and Coping With Perceived Risk to a Child
Sponsor:
National Human Genome Research Institute NHGRI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Parents With Bipolar Disorder Relationship of Adaptation to Own Illness With Risk Perception and Coping With Perceived Risk to a Child
Status:
COMPLETED
Status Verified Date:
2013-06-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Background
Bipolar disorder is a common mood disorder that affects 1 to 2 of the population Individuals with bipolar disorder tend to have periods of mania that are characterized by extra energy very poor judgment or unrealistic beliefs about their thoughts and abilities and an inability to complete thoughts and tasks as well as major depressive episodes The range and frequency of symptoms in affected individuals can vary greatly Most individuals have cyclical symptoms and spend more time in a normal mood state than in an overtly symptomatic state
Relatives of individuals with bipolar disorder have an increased risk for bipolar disorder and other mood disorders Currently risk assessment for recurrence of a mood disorder is based on family and medical histories genetic testing has not proved particularly useful to date for assessing risks of a mood disorder
Despite its prevalence there is limited research on coping with bipolar illness No published studies have examined adaptation to living with bipolar disorder or risk for bipolar disorder More specifically though a positive family history is the most important known risk factor for bipolar disorder there are no published studies about response to the threat of future illness onset in children risk modification efforts undertaken by affected parents or coping with the risk for illness in children
Objectives
To examine parents appraisals of the impact and cause of bipolar disorder and the association with their perceived risk for bipolar illness in their child and how they cope with their perception of risk to their child
To assess whether parents adaptation to their own illness is associated with coping with perceived risk to their child
To describe parents coping strategies related to perceived risk in their children
Eligibility
- Men and women at least 18 years of age who have been diagnosed with bipolar disorder and who have at least one biological child 30 years of age or younger Participants must be a primary caregiver for their children
Design
Participants in this study will take an online survey and answer questions about disease perceptions coping strategies and adapting to a diagnosis of bipolar disorder addressing issues such as the following
Assessing the threat of bipolar disorder and coping with one s own illness
Optimismpessimism of the individual coping with the illness
Perception of risk to a child and coping with the perceived risk
Data from this study will not be shared with the participantsrespondents
Bipolar disorder is a common mood disorder that affects 1 to 2 of the population Individuals with bipolar disorder tend to have periods of mania that are characterized by extra energy very poor judgment or unrealistic beliefs about their thoughts and abilities and an inability to complete thoughts and tasks as well as major depressive episodes The range and frequency of symptoms in affected individuals can vary greatly Most individuals have cyclical symptoms and spend more time in a normal mood state than in an overtly symptomatic state
Relatives of individuals with bipolar disorder have an increased risk for bipolar disorder and other mood disorders Currently risk assessment for recurrence of a mood disorder is based on family and medical histories genetic testing has not proved particularly useful to date for assessing risks of a mood disorder
Despite its prevalence there is limited research on coping with bipolar illness No published studies have examined adaptation to living with bipolar disorder or risk for bipolar disorder More specifically though a positive family history is the most important known risk factor for bipolar disorder there are no published studies about response to the threat of future illness onset in children risk modification efforts undertaken by affected parents or coping with the risk for illness in children
Objectives
To examine parents appraisals of the impact and cause of bipolar disorder and the association with their perceived risk for bipolar illness in their child and how they cope with their perception of risk to their child
To assess whether parents adaptation to their own illness is associated with coping with perceived risk to their child
To describe parents coping strategies related to perceived risk in their children
Eligibility
- Men and women at least 18 years of age who have been diagnosed with bipolar disorder and who have at least one biological child 30 years of age or younger Participants must be a primary caregiver for their children
Design
Participants in this study will take an online survey and answer questions about disease perceptions coping strategies and adapting to a diagnosis of bipolar disorder addressing issues such as the following
Assessing the threat of bipolar disorder and coping with one s own illness
Optimismpessimism of the individual coping with the illness
Perception of risk to a child and coping with the perceived risk
Data from this study will not be shared with the participantsrespondents
Detailed Description:
Though psychiatric disorders are extremely common and individuals with bipolar disorder have reproductive fitness approaching population rates we know very little about the perceptions and coping of parents with bipolar disorder related to their at-risk children Bipolar disorder is an etiologically-complex psychiatric disorder that is caused by a combination of genetic and environmental risk factors This study proposes to assess perceptions of parents with bipolar disorder about their illness response to illness threat and concerns about their children s risks We then propose to assess whether those appraisals are associated with the outcomes of coping strategies and adaption As informed by the Transactional Theory of Stress and Coping we propose to use a web-based survey to examine disease perceptions coping strategies and adaptation to the disorder Respondents will be recruited through the National Alliance of the Mentally Ill NAMI The study is cross-sectional and the survey is composed of several valid and reliable scales to measure the constructs predicted to be involved in adaptation Open-ended questions are included to help interpret results from the measures Knowledge about parents perceptions and coping with their own illness and with risk to children may lead to studies of potential coping interventions Ultimately downstream studies may help to improve parents adaptation to their own condition and how successfully they are able to manage concerns about perceived risks to their child
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 10-HG-N007 | None | None | None |