Ignite Creation Date:
2024-05-05 @ 11:26 AM
Last Modification Date:
2024-10-26 @ 9:07 AM
Study NCT ID:
NCT00046124
Status:
COMPLETED
Last Update Posted:
2006-09-04
First Post:
2002-09-20
Brief Title:
Organophosphate Pesticides and Human Reproductive Health
Sponsor:
National Institute of Environmental Health Sciences NIEHS
Organization:
National Institute of Environmental Health Sciences NIEHS
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2006-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This prospective cohort study assesses the effects of exposure to organophosphate OP pesticides on adverse reproductive outcomes in both male and female agricultural workers in China We will enroll women and their spouses who are attempting to become pregnant and observe reproductive endpoints including 1 semen parameters concentration total count motility progression and morphology 2 menstrual disorders oligomenorrhea amenorrhea polymenorrhea intermenstrual bleeding prolonged menstrual bleeding dysmenorrhea and irregular menstruation 3 alterations in hormone patterns including reduced estrogen excretion REE anovulation abnormal luteal phase ALP and abnormal follicular phase AFP in women and abnormalities of LH FSH TSH SHBG inhibin-B and testosterone in men 4 fecundability and 5 pregnancy outcomes including spontaneous abortion preterm delivery low birth weight and intrauterine growth retardation
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None