Ignite Creation Date:
2024-05-05 @ 11:26 AM
Last Modification Date:
2024-10-26 @ 9:07 AM
Study NCT ID:
NCT00044174
Status:
COMPLETED
Last Update Posted:
2024-07-15
First Post:
2002-08-20
Brief Title:
Dyadic Interactions in Depressed and Non-Depressed Mothers and Their Infants
Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Dyadic Interactions in Depressed and Non-Depressed Mothers With Their Infants
Status:
COMPLETED
Status Verified Date:
2024-03-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will examine 1 differences among mothers behaviors and how these behaviors influence their infants reactions and 2 how mother-child interactions relate to children s temperament and cognitive thought processing abilities and other areas of development
Depressed and non-depressed English-speaking mothers between 20 and 45 years of age with an infant 4 months or younger may be eligible for this study Candidates will be screened with a mailed survey regarding their moods and feelings Participants will undergo the following procedures
Psychiatric Interview Subjects will participate in a 30-90 minute interview consisting of a series of standardized questions about the their behaviors and feelings Participants whose interviews suggest a condition that may impact their mental health will be referred to the study clinician for follow-up to confirm or clarify the preliminary findings Continued participation in the study will be determined following this
Home Visit A study investigator will visit the home for 1 hour to film the mother and baby during the mother s typical daily activities This visit will take place when the baby is about 5 months old At the end of the visit the mother will be given a variety of surveys to fill out at home and return at the next visit see Lab Visit below The survey questions deal with the mother s relationship with her partner support from people in her life typical behaviors of her infant and how often she feels certain emotions A packet of surveys will also be left for the participant s partner to complete and mail back to the investigator The partner may or may not be the child s biological father and may or may not choose to participate in the study
Lab Visit Within 1 week of the home visit the mother and child will come to the NICHD clinic for about 2 hours During this time the mother will return the previous surveys and fill out another one regarding her current mood She will then interact with her child who will be seated in front of her The 20-minute session will be videotaped There will be breaks during the session The mother will be instructed about how she should act happy or sad She and her baby will then participate in a variety of filmed situations that will induce certain emotions in the baby such as happiness fear activity frustration and interest in order to learn how different children react to different situations
Participants will be contacted to continue the study when their babies are 12 months old and again when the children are 24 months old The above procedures will be repeated and some new measures will be added for toddlers that involve activities investigating aspects of early language and social reasoning
Depressed and non-depressed English-speaking mothers between 20 and 45 years of age with an infant 4 months or younger may be eligible for this study Candidates will be screened with a mailed survey regarding their moods and feelings Participants will undergo the following procedures
Psychiatric Interview Subjects will participate in a 30-90 minute interview consisting of a series of standardized questions about the their behaviors and feelings Participants whose interviews suggest a condition that may impact their mental health will be referred to the study clinician for follow-up to confirm or clarify the preliminary findings Continued participation in the study will be determined following this
Home Visit A study investigator will visit the home for 1 hour to film the mother and baby during the mother s typical daily activities This visit will take place when the baby is about 5 months old At the end of the visit the mother will be given a variety of surveys to fill out at home and return at the next visit see Lab Visit below The survey questions deal with the mother s relationship with her partner support from people in her life typical behaviors of her infant and how often she feels certain emotions A packet of surveys will also be left for the participant s partner to complete and mail back to the investigator The partner may or may not be the child s biological father and may or may not choose to participate in the study
Lab Visit Within 1 week of the home visit the mother and child will come to the NICHD clinic for about 2 hours During this time the mother will return the previous surveys and fill out another one regarding her current mood She will then interact with her child who will be seated in front of her The 20-minute session will be videotaped There will be breaks during the session The mother will be instructed about how she should act happy or sad She and her baby will then participate in a variety of filmed situations that will induce certain emotions in the baby such as happiness fear activity frustration and interest in order to learn how different children react to different situations
Participants will be contacted to continue the study when their babies are 12 months old and again when the children are 24 months old The above procedures will be repeated and some new measures will be added for toddlers that involve activities investigating aspects of early language and social reasoning
Detailed Description:
Maternal depression is a concurrent and longitudinal risk factor for children s development Maternal depression exerts direct effects and indirect effects through proximal processes of mother-child dyadic interactions Both depressed mothers and their infants are inattentive unresponsive affectively flat and disengaged during naturalistic interactions and their dyadic interactions have been described as less synchronous Our primary objective is to investigate differences between depressed and non-depressed dyads in maternal behaviors child behaviors and dyadic behaviors in terms of latency synchrony and contingency In the present study we propose to examine the determinants and effects of dyadic interactions of depressed and nondepressed mothers with their infants across several domains of child development We plan to replicate and extend previous work by observing the dyads in naturalistic as well as experimental face-to-face settings at 5 12 and 24 months
Groups of depressed and nondepressed mothers will be selected on the basis of self-reports of depressive symptoms and by clinical diagnostic interviews These assessments will be repeated at 12 and 24 months to assess the course of maternal depression The study consists of a home visit a lab visit and administration of questionnaires to mothers and their spouses or partners at three time points All maternal and child behaviors during dyadic interactions will be coded as continuous streams of data for analysis of reciprocal influences within the dyad By coding a range of behaviors such as facial affect vocalization physical activity and visual attention of the mother and infant we hope to capture variations in mother-child interactions both between and within depressed and nondepressed dyads Differences in styles of dyadic interactions have been shown to have important consequences on subsequent child development in several domains In addition experimental simulations will consist of instructed depressed and happy simulations of mothers with their infants Specific simulations allow observation of changes in infant behaviors from the spontaneous episodes and comparison between depressed and nondepressed dyads
Understanding the context of child development both normative and atypical is important as means of elucidating the processes by which maternal depression operates as a risk factor for children s cognitive and socioemotional development Several socio-demographic and psychosocial factors will be assessed by maternal and paternal self-reports to examine which factors exacerbate or buffer the effects of maternal depression In addition to modifying the observations of maternal and child behaviors to be age-appropriate new measures will be introduced at 12 and 24 months to capture child s functioning in multiple areas
Groups of depressed and nondepressed mothers will be selected on the basis of self-reports of depressive symptoms and by clinical diagnostic interviews These assessments will be repeated at 12 and 24 months to assess the course of maternal depression The study consists of a home visit a lab visit and administration of questionnaires to mothers and their spouses or partners at three time points All maternal and child behaviors during dyadic interactions will be coded as continuous streams of data for analysis of reciprocal influences within the dyad By coding a range of behaviors such as facial affect vocalization physical activity and visual attention of the mother and infant we hope to capture variations in mother-child interactions both between and within depressed and nondepressed dyads Differences in styles of dyadic interactions have been shown to have important consequences on subsequent child development in several domains In addition experimental simulations will consist of instructed depressed and happy simulations of mothers with their infants Specific simulations allow observation of changes in infant behaviors from the spontaneous episodes and comparison between depressed and nondepressed dyads
Understanding the context of child development both normative and atypical is important as means of elucidating the processes by which maternal depression operates as a risk factor for children s cognitive and socioemotional development Several socio-demographic and psychosocial factors will be assessed by maternal and paternal self-reports to examine which factors exacerbate or buffer the effects of maternal depression In addition to modifying the observations of maternal and child behaviors to be age-appropriate new measures will be introduced at 12 and 24 months to capture child s functioning in multiple areas
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 02-CH-0278 | None | None | None |