Ignite Creation Date:
2024-05-05 @ 10:01 PM
Last Modification Date:
2024-10-26 @ 10:13 AM
Study NCT ID:
NCT01016938
Status:
COMPLETED
Last Update Posted:
2019-08-19
First Post:
2009-11-19
Brief Title:
Dynamic Magnetic Resonance Imaging MRI for Lung Tumor Motion and Lung Function GCC 0943
Sponsor:
University of Maryland Baltimore
Organization:
University of Maryland Baltimore
Study Overview
Official Title:
Dynamic MRI for Lung Tumor Motion and Lung Function
Status:
COMPLETED
Status Verified Date:
2019-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Radiation treatment for each patient with cancer is designed based on CT scans We know that tumors in the chest and abdomen move when you breathe Because of this there can be differences between planned treatment and the treatment actually delivered to the body Usually with radiation a safety margin is added to ensure that radiation hits the entire tumor This can damage healthy parts of the body because the exact location of the tumor is unknown
Magnetic resonance imaging MRI is a painless and safe diagnostic procedure that uses a powerful magnet and radio waves to produce detailed images of the bodys organs and structures without the use of X-rays or other radiation
The research doctors are studying to see if the position of a tumor can be tracked using MRI scans and tracking sensors placed on the skin MRI scans and the tracking system used to calculate the location and position of the tumor are both FDA approved technologies
The research doctors will also use the MRI scans to evaluate any changes in your lung function during and following your radiation treatments
In this study the participant will undergo a series of MRI scans with and without contrast dye
This study is being funded through grants from the National Institutes of Health NIH
Magnetic resonance imaging MRI is a painless and safe diagnostic procedure that uses a powerful magnet and radio waves to produce detailed images of the bodys organs and structures without the use of X-rays or other radiation
The research doctors are studying to see if the position of a tumor can be tracked using MRI scans and tracking sensors placed on the skin MRI scans and the tracking system used to calculate the location and position of the tumor are both FDA approved technologies
The research doctors will also use the MRI scans to evaluate any changes in your lung function during and following your radiation treatments
In this study the participant will undergo a series of MRI scans with and without contrast dye
This study is being funded through grants from the National Institutes of Health NIH
Detailed Description:
In this protocol we seek to assess whether tumor motion can be inferred using dynamic MRI and external surrogates We propose to 1 investigate the feasibility of tracking the real-time tumor position using dynamic MRI and inferring tumor position using external surrogates placed on the skin of the subject and 2 determine lung function during and following radiation by assessing lung perfusion maps obtained via dynamic MRI with dose maps in order to determine image-based biomarkers for lung toxicity following radiation therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None