Ignite Creation Date:
2025-12-24 @ 11:42 PM
Ignite Modification Date:
2025-12-28 @ 10:36 PM
Study NCT ID:
NCT04845451
Status:
COMPLETED
Last Update Posted:
2022-11-30
First Post:
2021-04-10
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Presence and Role of Zygomatic-temporal Neuroma Triggering Cluster Headache
Sponsor:
FARO T. OWIESY, M.D
Organization:
Study Overview
Official Title:
The Presence and Role of Zygomatic-temporal Neuroma Triggering Cluster Headache: Resection of a Neuroma in the Long-term Resolution of Trigeminal Cluster Symptoms
Status:
COMPLETED
Status Verified Date:
2022-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Role of a neuroma of zygomatic-temporal in triggering of a cluster headache. Exploratory diagnosis, resection, and pathological examination of tumor anticipated
.
.
Detailed Description:
An anatomical coordinated communication of a Cluster Circuit turned on by Zygomatico-Temporal neuroma, a malicious possibly nontraumatic, neoplastic tissue coding and decoding itself upon autonomic release of neurotransmitter(s). Exhaustion of neurotransmitter synthesis turns out the explosions of pain-symptoms off.
Poor attention to the characterization of a peripheral neuroma of trigeminal nerve branch deranged attention to central(CNS) characterization of Cluster Symptoms.
This study based on our experimental results of minimal surgical procedure to explore, diagnose and resect a Zygomatico-Temporal neuroma in the temple of patients suffering from EpisodicChronic, Cluster Headache-ECCH. The goal is to light on this speculation in a novel analysis of events to put an end to devastating catastrophic headaches. Detailed anatomical components loci of the autonomic symptoms in the cluster headache reveal the presence of an electrical neural circuit.
The extracranial circuit components of ECCH reflects the anatomical nerve components participating reflection of the single circumscribed symptom:
1. Zygomatico-Temporal-neuroma
2. Zygomatic nerve V-II
3. Intraorbital communicants rami
4. Lacrimal nerve V-I
5. Ophthalmic nerve Intraorbital routing, supraorbital nerves, the upper eyelid, the conjunctiva and cornea of the eye, the nose (including the tip of the nose, except alae nasi), the nasal mucosa, the frontal sinuses. V-I
6. Optic nerve via ophthalmic nerve routing and electricity propagation.
7. Pterygopalatine ganglion as peripheral and CNS coordinator center.
An intracranial CNS reaction follows in response to the perception of pain materialized in neuroimaging during the activity of ECCH.
Poor attention to the characterization of a peripheral neuroma of trigeminal nerve branch deranged attention to central(CNS) characterization of Cluster Symptoms.
This study based on our experimental results of minimal surgical procedure to explore, diagnose and resect a Zygomatico-Temporal neuroma in the temple of patients suffering from EpisodicChronic, Cluster Headache-ECCH. The goal is to light on this speculation in a novel analysis of events to put an end to devastating catastrophic headaches. Detailed anatomical components loci of the autonomic symptoms in the cluster headache reveal the presence of an electrical neural circuit.
The extracranial circuit components of ECCH reflects the anatomical nerve components participating reflection of the single circumscribed symptom:
1. Zygomatico-Temporal-neuroma
2. Zygomatic nerve V-II
3. Intraorbital communicants rami
4. Lacrimal nerve V-I
5. Ophthalmic nerve Intraorbital routing, supraorbital nerves, the upper eyelid, the conjunctiva and cornea of the eye, the nose (including the tip of the nose, except alae nasi), the nasal mucosa, the frontal sinuses. V-I
6. Optic nerve via ophthalmic nerve routing and electricity propagation.
7. Pterygopalatine ganglion as peripheral and CNS coordinator center.
An intracranial CNS reaction follows in response to the perception of pain materialized in neuroimaging during the activity of ECCH.
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: