Ignite Creation Date:
2024-05-05 @ 9:57 PM
Last Modification Date:
2024-10-26 @ 10:11 AM
Study NCT ID:
NCT00994006
Status:
COMPLETED
Last Update Posted:
2011-05-04
First Post:
2009-10-11
Brief Title:
The Absorption of Magnesium Oxide Compared to Citrate in Healthy Subjects
Sponsor:
Sheba Medical Center
Organization:
Sheba Medical Center
Study Overview
Official Title:
The Absorption of Supplemental Magnesium Oxide Compared to Magnesium Citrate in Healthy Subjects With no Apparent Heart Disease
Status:
COMPLETED
Status Verified Date:
2011-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The magnesium food content in the Western world is consistently reducing Hypomagnesemia is common in hospitalized patients especially in the elderly with coronary artery disease CAD andor those with chronic heart failure Hypomagnesemia is associated with increased incidence of diabetes mellitus metabolic syndrome mortality rate from coronary artery disease CAD and all cause Magnesium supplementation improves myocardial metabolism inhibits calcium accumulation and myocardial cell death it improves vascular tone peripheral vascular resistance afterload and cardiac output reduces cardiac arrhythmias and improves lipid metabolism Magnesium also reduces vulnerability to oxygen-derived free radicals improves human endothelial function and inhibits platelet function including platelet aggregation and adhesion The data regarding the absorption difference between supplemental magnesium oxide and magnesium citrate in humans is spare
Detailed Description:
Two oral preparations of magnesium are available in Israel
1 Magnesium Diasporal magnesium citrate elemental magnesium 986 mg PROTINA GMBH ISMANING Germany
2 Magnox 520 TM magnesium oxide 520 mg elemental magnesium Naveh Pharma Ltd Israel
The data regarding the absorption difference between the two supplemental magnesium preparations magnesium oxide and magnesium citrate in humans is spare
Primary objective To find out the absorption of magnesium citrate compared to magnesium oxide in healthy subjects with no apparent heart disease
1 Magnesium Diasporal magnesium citrate elemental magnesium 986 mg PROTINA GMBH ISMANING Germany
2 Magnox 520 TM magnesium oxide 520 mg elemental magnesium Naveh Pharma Ltd Israel
The data regarding the absorption difference between the two supplemental magnesium preparations magnesium oxide and magnesium citrate in humans is spare
Primary objective To find out the absorption of magnesium citrate compared to magnesium oxide in healthy subjects with no apparent heart disease
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None