Ignite Creation Date:
2024-05-05 @ 11:26 AM
Last Modification Date:
2024-10-26 @ 9:07 AM
Study NCT ID:
NCT00043615
Status:
COMPLETED
Last Update Posted:
2017-07-02
First Post:
2002-08-09
Brief Title:
Collection of Blood Bone Marrow Tumor or Tissue Samples
Sponsor:
National Cancer Institute NCI
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Acquisition of Blood Bone Marrow Tumor or Tissue Samples
Status:
COMPLETED
Status Verified Date:
2012-04-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will collect biological samples-blood bone marrow tumor or other tissue samples-for use in cancer-related research The specimens will be used for various tests of drug resistance blood vessel formation cancer-causing proteins and immune functions The purpose is to identify steps in the cancer development process that may serve as targets for treatment and to test various therapies for current and future cancer treatment clinical trials
Individuals 18 years of age and older with cancer or a pre-cancerous condition such as colon polyps or cervical dysplasia are eligible for this study as are patients at high risk for cancer In addition patients who do not have cancer but require surgery biopsy or other procedure for another medical reason may be included as normal specimen donors
Participants will have about 40 milliliters 3 tablespoons of blood drawn upon entering the study and additional 40-ml samples drawn periodically during the course of treatment No more than 120 ml of blood will be drawn over a 12-month period Some patients may require a surgical procedure or biopsy removal of tumor tissue for medical reasons or as part of their enrollment in a research treatment study In such cases a portion of the specimens collected during those procedures will be used for the research studies in this protocol
Individuals 18 years of age and older with cancer or a pre-cancerous condition such as colon polyps or cervical dysplasia are eligible for this study as are patients at high risk for cancer In addition patients who do not have cancer but require surgery biopsy or other procedure for another medical reason may be included as normal specimen donors
Participants will have about 40 milliliters 3 tablespoons of blood drawn upon entering the study and additional 40-ml samples drawn periodically during the course of treatment No more than 120 ml of blood will be drawn over a 12-month period Some patients may require a surgical procedure or biopsy removal of tumor tissue for medical reasons or as part of their enrollment in a research treatment study In such cases a portion of the specimens collected during those procedures will be used for the research studies in this protocol
Detailed Description:
Patients will be evaluated at NNMC Clinics Blood samples may be collected at the initial visit and at follow-up visits Tumor samples may be obtained by fine needle aspirate by removal of pleural or peritoneal fluid or by excisional biopsy or other procedure In general biopsy tissue will be obtained as an additional sample at the time of a medically indicated procedure In some cases a biopsy may be performed only to obtain a research sample providing the tumor is accessible with a minimal risk to the patient Specific risks will be described in a separate consent to be obtained at the time of the biopsy Tumor samples and blood samples will be processed andor stored for use in research efforts in the laboratories of the Medical Oncology Branch Experimental Transplant and Immunology Branch or Genetics Branch Center for Cancer Research NCI at Navy and NIH
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 02-C-0258 | None | None | None |