Ignite Creation Date:
2024-05-05 @ 9:48 PM
Last Modification Date:
2024-10-26 @ 10:09 AM
Study NCT ID:
NCT00967408
Status:
UNKNOWN
Last Update Posted:
2009-08-27
First Post:
2009-08-26
Brief Title:
Effects on Clinical and Functional Outcome of Escitalopram in Adult Stroke Patients
Sponsor:
Azienda Ospedaliero Universitaria Maggiore della Carita
Organization:
Azienda Ospedaliero Universitaria Maggiore della Carita
Study Overview
Official Title:
Effects on Clinical and Functional Outcome of Escitalopram in Adult Stroke
Status:
UNKNOWN
Status Verified Date:
2009-08
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Rehabilitative treatment in stroke survivors has shown to be effective in improving functional outcome and reducing dependency Plasticity of the central nervous system along with coping strategies and adaptations seems to play a key role in functional recovery Some data support the hypothesis that drug which improve dopaminergic serotoninergic and noradrenergic transmission in the central nervous system could improve recovery in stroke patients In this population antidepressants as selective serotonin reuptake inhibitors SSRI are associated to better outcomes as evidenced by small clinical trials However since depression is a common consequence of stroke observed improvements could be biased by the action of these drugs on depressive symptoms thus improving participation in rehabilitative treatment
The hypothesis of this study is that SSRI could improve functional outcome in stroke survivors not only because of their action on depressive symptoms but mainly because of a direct effect on neural repair and neuronal growth
The aim of the study is to evaluate the effect of a SSRI escitalopram on functional outcome of stroke patients
The hypothesis of this study is that SSRI could improve functional outcome in stroke survivors not only because of their action on depressive symptoms but mainly because of a direct effect on neural repair and neuronal growth
The aim of the study is to evaluate the effect of a SSRI escitalopram on functional outcome of stroke patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None