Ignite Creation Date:
2025-12-26 @ 12:19 PM
Ignite Modification Date:
2025-12-31 @ 12:49 PM
Study NCT ID:
NCT07039500
Status:
RECRUITING
Last Update Posted:
2025-08-07
First Post:
2025-06-06
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Impact of Severe Obstructive Sleep Apnea-Hypopnea Syndrome on Auditory-Cognitive Processing
Sponsor:
Peking University First Hospital
Organization:
Study Overview
Official Title:
Impact of Severe Obstructive Sleep Apnea-Hypopnea Syndrome on Auditory-Cognitive Processing
Status:
RECRUITING
Status Verified Date:
2024-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this observational study is to learn how severe obstructive sleep apnea-hypopnea syndrome (OSAHS) affects the brain's ability to process sounds and attention in adults aged 20-60 years. The main questions it aims to answer are:
1. Does severe OSAHS change how the brain automatically detects sound changes during wakefulness?
2. Does severe OSAHS reduce people's ability to pay attention to important sounds when awake?
3. Can brainwave tests (Electroencephalogram, EEG) detect early signs of hearing-related cognitive problems in OSAHS patients before symptoms appear?
Researchers will compare two groups:
* 50 adults with severe OSAHS (diagnosed by sleep tests)
* 50 healthy adults matched by age and gender
Participants will:
* Complete hearing tests (MoCA)
* Undergo a 1-night sleep test (PSG)
* Wear an EEG cap for 1.5-2 hours while listening to sounds in a quiet room:
* Passive task: Relax (no response needed)
* Active task: Press a button when hearing rare sounds
* Receive ¥75/hour compensation for their time
1. Does severe OSAHS change how the brain automatically detects sound changes during wakefulness?
2. Does severe OSAHS reduce people's ability to pay attention to important sounds when awake?
3. Can brainwave tests (Electroencephalogram, EEG) detect early signs of hearing-related cognitive problems in OSAHS patients before symptoms appear?
Researchers will compare two groups:
* 50 adults with severe OSAHS (diagnosed by sleep tests)
* 50 healthy adults matched by age and gender
Participants will:
* Complete hearing tests (MoCA)
* Undergo a 1-night sleep test (PSG)
* Wear an EEG cap for 1.5-2 hours while listening to sounds in a quiet room:
* Passive task: Relax (no response needed)
* Active task: Press a button when hearing rare sounds
* Receive ¥75/hour compensation for their time
Detailed Description:
None
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: