Ignite Creation Date:
2025-12-26 @ 11:47 AM
Ignite Modification Date:
2025-12-26 @ 11:47 AM
Study NCT ID:
NCT07103616
Status:
NOT_YET_RECRUITING
Last Update Posted:
2025-08-05
First Post:
2025-07-29
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4
Sponsor:
Children's Hospital Los Angeles
Organization:
Study Overview
Official Title:
Individual Cerebral Hemodynamic Oxygenation Relationships - ICHOR 4
Status:
NOT_YET_RECRUITING
Status Verified Date:
2025-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ICHOR
Brief Summary:
The goal of this clinical trial is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two types of anesthesia: Propofol or Dexmedetomidine. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of Propofol and Dexmedetomidine are in clinical equipoise will be offered to have the anesthesia they will receive during their MRI randomized.
* Change in cerebral blood flow (ml blood/100g/min)
* Change in cerebral metabolic rate of oxygen (ml O2/100g/min)
Researchers will compare Propofol (Group A) to Dexmedetomidine (Group B) to see if compare the hemodynamic response to anesthesia.
Participants will be randomized to receive one of two equally safe anesthetics (Propofol or Dexmedetomidine).
* Change in cerebral blood flow (ml blood/100g/min)
* Change in cerebral metabolic rate of oxygen (ml O2/100g/min)
Researchers will compare Propofol (Group A) to Dexmedetomidine (Group B) to see if compare the hemodynamic response to anesthesia.
Participants will be randomized to receive one of two equally safe anesthetics (Propofol or Dexmedetomidine).
Detailed Description:
None
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| 5K25HL153954-03 | NIH | None | https://reporter.nih.gov/quic… | View |