Ignite Creation Date:
2025-12-26 @ 11:08 AM
Ignite Modification Date:
2025-12-31 @ 12:45 PM
Study NCT ID:
NCT00524212
Status:
COMPLETED
Last Update Posted:
2010-01-20
First Post:
2007-08-31
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
How to Improve Diagnosis in Infective Endocarditis
Sponsor:
University of Aarhus
Organization:
Study Overview
Official Title:
Ph. D Student, Jane Byriel Knudsen, Aarhus University
Status:
COMPLETED
Status Verified Date:
2010-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose is to exam prospective if simple clinical information in combination with a normal s-procalcitonin are sufficient for exclusion of infective endocarditis (IE).
Detailed Description:
Despite progress in surgical and medical treatment, infective endocarditis is still associated with high morbidity and mortality.
The variable clinical presentation of IE makes the diagnosis a clinical challenge.
Procalcitonin is a precursor from the hormone calcitonin and also a marker of systemic bacterial infections.
The purpose of this study is:
* to investigate the diagnostic value of serum procalcitonin (PCT), C-reactive protein (CRP) and sedimentation rate (SR) when IE is suspected.
* to investigate if a retrospectively generated clinical model suitable for exclusion of IE can be confirmed prospectively.
The variable clinical presentation of IE makes the diagnosis a clinical challenge.
Procalcitonin is a precursor from the hormone calcitonin and also a marker of systemic bacterial infections.
The purpose of this study is:
* to investigate the diagnostic value of serum procalcitonin (PCT), C-reactive protein (CRP) and sedimentation rate (SR) when IE is suspected.
* to investigate if a retrospectively generated clinical model suitable for exclusion of IE can be confirmed prospectively.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: