Ignite Creation Date:
2024-05-05 @ 9:42 PM
Last Modification Date:
2024-10-26 @ 10:08 AM
Study NCT ID:
NCT00947050
Status:
COMPLETED
Last Update Posted:
2010-10-26
First Post:
2009-07-24
Brief Title:
Prompt Human Coronary Collateral Vasomotor Function Induced by Dynamic Physical Exercise
Sponsor:
Insel Gruppe AG University Hospital Bern
Organization:
Insel Gruppe AG University Hospital Bern
Study Overview
Official Title:
Prompt Human Coronary Collateral Vasomotor Function Induced by Dynamic Physical Exercise
Status:
COMPLETED
Status Verified Date:
2010-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study in humans with stable coronary artery disease CAD treatable by PCI percutaneous coronary intervention is to evaluate if dynamic physical exercise leads to an instantaneous improvement of coronary collateral function
Detailed Description:
The existence of coronary collateral vessels and their benefit against cardiac events have been recognized for many years but their functional capacity in response to physical exercise has partially remained elusive Via endothelial shear stress the fundamental stimulus for collateral development exercise theoretically leads to collateral vasodilation and recruitment by an increase in heart rate and blood pressure during exercise Moreover the phenomenon of walking through angina indicates that collateral function and physical activity are related and their interaction is of clinical relevance
The purpose of the present study in humans with stable coronary artery disease was to assess the instantaneous response of coronary collateral function to dynamic physical exercise
The purpose of the present study in humans with stable coronary artery disease was to assess the instantaneous response of coronary collateral function to dynamic physical exercise
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None