Ignite Creation Date:
2024-05-05 @ 11:25 AM
Last Modification Date:
2024-10-26 @ 9:07 AM
Study NCT ID:
NCT00032500
Status:
COMPLETED
Last Update Posted:
2006-08-18
First Post:
2002-03-22
Brief Title:
Evaluation of Echinacea for the Common Cold
Sponsor:
National Center for Complementary and Integrative Health NCCIH
Organization:
National Center for Complementary and Integrative Health NCCIH
Study Overview
Official Title:
Evaluation of Echinacea in a Human Rhinovirus Challenge
Status:
COMPLETED
Status Verified Date:
2006-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine whether three Echinacea preparations with different chemical compositions are effective for prevention or treatment of the common cold
Detailed Description:
Echinacea is a widely used herbal remedy for the common cold Previous clinical trials designed to assess the efficacy of Echinacea for prevention or treatment of the common cold have produced inconsistent results A variety of different Echinacea products have been used in these clinical trials Recent studies indicate that different Echinacea preparations have dramatically different phytochemical profiles The available clinical trial data provide no information about the potential role of the different constituents of Echinacea in common cold prevention or treatment Our hypothesis is that the variation in reported clinical effectiveness may be due to differences in the phytochemical profile of the Echinacea preparations used This study will address the following specific aims 1 Evaluate the effectiveness of chemically defined extracts of E angustifolia root which contain alkamides echinacoside or polysaccharidelglycoprotein for common cold prevention or treatment 2 Assess the correlation between specific Echinacea metabolites in serum and nasal secretions and efficacy for prevention and treatment of colds and 3 Determine the effect of different Echinacea preparations on the host response to rhinovirus infection
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None