Ignite Creation Date:
2024-05-05 @ 9:27 PM
Last Modification Date:
2024-10-26 @ 10:04 AM
Study NCT ID:
NCT00882648
Status:
COMPLETED
Last Update Posted:
2013-02-21
First Post:
2009-04-15
Brief Title:
The Effect of Fetal Gender on Maternal Substance Abuse Treatment
Sponsor:
Johns Hopkins University
Organization:
Johns Hopkins University
Study Overview
Official Title:
The Effect of Fetal Gender on Maternal Substance Abuse Treatment
Status:
COMPLETED
Status Verified Date:
2013-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Previous studies by this team of investigators has determined that male infants are more likely to display more severe neonatal abstinence syndrome NAS as a result of maternal opioid use during pregnancy Jansson 2007and there is appears to be a gender-related biologic vulnerability to NAS expression Jansson 2009 submitted The proposed study explores the relationship between fetal gender and substance abuse treatment outcomes among a population of women in comprehensive substance abuse treatment to explore the possibility of a psychosocial vulnerability among drug exposed male fetuses as opposed to female fetuses Women in substance abuse treatment are a group at high risk for current exposure to violence usually at the hands of significant others and having a history of sexual abuse as a child usually resulting from contact with a male family member Therefore they often have difficult relationships with men At the Center for Addiction and Pregnancy CAP a 2006 study revealed that among a group of 715 pregnant women reports of the exposure to violence was very high Their rates of lifetime abuse ranged from 727 for physical abuse to 445 for sexual abuse Rates of abuse remained high during their current pregnancy ranging from 20 for physical abuse to 71 for sexual abuse Velez 2006 The abuse was very often at the hands of partners or other male family member perpetrators We hypothesize that women carrying male fetuses will be less likely to remain complaint in drug treatment or abstinent from illicit drug use while women carrying female fetuses may be more likely to remain drug abstinent and treatment compliant If supported this theory has the potential to inform fetal gender specific treatment for pregnant drug dependent women Additionally we seek to support the previously documented link between male gender and more severe expression of NAS and explore the relationship between other maternal prescribed drug use ie psychotropic medications and severity of NAS expression
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01DA019934 | NIH | None | httpsreporternihgovquickSearchR01DA019934 |