Ignite Creation Date:
2025-12-24 @ 10:59 PM
Ignite Modification Date:
2025-12-25 @ 8:28 PM
Study NCT ID:
NCT05473169
Status:
UNKNOWN
Last Update Posted:
2022-07-25
First Post:
2021-12-21
Is NOT Gene Therapy:
False
Has Adverse Events:
False
Brief Title:
Swallowing Evaluation in VF Immobility
Sponsor:
Assiut University
Organization:
Study Overview
Official Title:
Evaluation of Swallowing in Patients With Vocal Folds Immobility
Status:
UNKNOWN
Status Verified Date:
2022-07
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Vocal fold immobility (VFI) often results in significant problems with dysphonia, dysphagia, and decreased cough strength. As one element of the dysphagia potentially associated with vocal fold immobility,
aspiration may create significant morbidity for these patients. An estimated 38% to 53% of patients with
untreated VFI have swallowing difficulties with aspiration.
Vocal fold immobility has important implication on the laryngeal airway protection during respiration,
phonation and swallowing. It is the most common neurological laryngeal disorder.
The immobility may be caused by neck and thoracic surgery. which can impair the innervation of the pharynx,
upper esophageal sphincter (U.E.S) and proximal esophagus but may also be due to malignancy,trauma,
Intracranial causes,or may be idiopathic
aspiration may create significant morbidity for these patients. An estimated 38% to 53% of patients with
untreated VFI have swallowing difficulties with aspiration.
Vocal fold immobility has important implication on the laryngeal airway protection during respiration,
phonation and swallowing. It is the most common neurological laryngeal disorder.
The immobility may be caused by neck and thoracic surgery. which can impair the innervation of the pharynx,
upper esophageal sphincter (U.E.S) and proximal esophagus but may also be due to malignancy,trauma,
Intracranial causes,or may be idiopathic
Detailed Description:
Besides the voice alteration, the lesion that causes of vocal fold immobility should also affect the pharyngeal phase of swallowing.
It was suggested that dysphagia in patient with vocal fold immobility has multifactor causes ; including limited airway protection and decrease laryngopharyngeal sensation based on the finding of the flexible endoscopy.
Another study revealed that pharyngeal phase abnormalities such as delayed initiation of swallowing, reduced laryngeal elevation, and reduced upper esophageal sphincter (UES) opening were found in video fluoroscopic swallowing studies (VFSS).
Several studies on the swallowing difficulties of patient with vocal fold immobility has been performed and reported that nearly 56% of these patients immobility have swallowing dysfunction.
It was suggested that dysphagia in patient with vocal fold immobility has multifactor causes ; including limited airway protection and decrease laryngopharyngeal sensation based on the finding of the flexible endoscopy.
Another study revealed that pharyngeal phase abnormalities such as delayed initiation of swallowing, reduced laryngeal elevation, and reduced upper esophageal sphincter (UES) opening were found in video fluoroscopic swallowing studies (VFSS).
Several studies on the swallowing difficulties of patient with vocal fold immobility has been performed and reported that nearly 56% of these patients immobility have swallowing dysfunction.
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: