Ignite Creation Date:
2024-05-05 @ 9:23 PM
Last Modification Date:
2024-10-26 @ 10:03 AM
Study NCT ID:
NCT00872456
Status:
COMPLETED
Last Update Posted:
2020-07-16
First Post:
2009-03-30
Brief Title:
Associations Between Diabetes Care and Haptoglobin Genotype On outComes
Sponsor:
Clalit Health Services
Organization:
Clalit Health Services
Study Overview
Official Title:
The ADHOC Project Associations Between Diabetes Care and Haptoglobin Genotype On outComes
Status:
COMPLETED
Status Verified Date:
2020-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ADHOC
Brief Summary:
The ADHOC Cohort comprised 3044 DM individuals treated in 47 CHS primary care clinics that underwent haptoglobin genotyping between 2 march 2005 and 26 September 2006 Individuals were eligible for inclusion if they had DM and were 55 years of age or older All treatment decisions regarding all aspects of care and follow-up of the study participants remained at the discretion of the individuals primary care physician who was blinded to the individuals Hp type Hp distribution was Hp 1-1 285 94 Hp 2-1 1248 410 Hp 2-2 1511 496
Hypothesis strict glucose control HbA1c7 reduces the rate of cardiovascular events only to diabetic patients with the Hp 2-2 phenotype We also postulated that since Hp 2-2 DM individuals are at an increased genetic susceptibility for cardiovascular disease CVD this unique cohort merits an investigation on the associations between various CVD risk variables and CVD events and establish whether any evident association was dependent of the individuals Hp type
Hypothesis strict glucose control HbA1c7 reduces the rate of cardiovascular events only to diabetic patients with the Hp 2-2 phenotype We also postulated that since Hp 2-2 DM individuals are at an increased genetic susceptibility for cardiovascular disease CVD this unique cohort merits an investigation on the associations between various CVD risk variables and CVD events and establish whether any evident association was dependent of the individuals Hp type
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None