Ignite Creation Date:
2024-05-05 @ 9:21 PM
Last Modification Date:
2024-10-26 @ 10:03 AM
Study NCT ID:
NCT00868270
Status:
UNKNOWN
Last Update Posted:
2009-03-24
First Post:
2009-03-22
Brief Title:
Urinary Cytokine Levels as a Prognostic Marker for Kidney Scarring After Pyelonephritis
Sponsor:
Hillel Yaffe Medical Center
Organization:
Hillel Yaffe Medical Center
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2009-03
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The prevalence of kidney scarring after UTI is approximately 5-57 UTIs are caused mainly by bacteria that cause local and systemic immunological reaction that are accompanied by cytokines These cytokines are a main factor in the inflammatory process They are produced by leukocytes macrophages fibroblasts endothelial cells and epithelial cells in the kidney tissue Interleukin 6 and 8 IL-6 IL-8 were found in high levels in the urine of children and adults who suffer from UTIs Other studies on animals have found a relationship between inflammatory reaction and scarring in the kidney We hypothesize that we will find a similar relationship between the level of IL-6 IL-8 in the urine during acute pyelonephritis in children and the probability of kidney scarring
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None