Ignite Creation Date:
2024-05-05 @ 11:24 AM
Last Modification Date:
2024-10-26 @ 9:06 AM
Study NCT ID:
NCT00028210
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
2001-12-17
Brief Title:
Enhanced Tactile Touch Spatial Acuity in Upper Limb Amputees
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Enhancement of Tactile Spatial Acuity in Upper Limb Amputees
Status:
COMPLETED
Status Verified Date:
2004-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will examine whether tactile touch abilities at the lip are more acute in people with upper limb amputation compared with healthy normal volunteers People with an amputated upper limb have an expanded brain representation of the lip that may correlate with heightened tactile spatial acuity
Normal volunteers will be recruited for this study Candidates will be screened with physical and neurological examinations Amputee volunteers will be studied at the amputee clinic at the University of Tubingen Germany
Participants will sit comfortably in a chair wearing a blindfold during the following experiments
Plastic domes with grooves are placed on parts of the lower lip on either side for a few seconds The volunteer is then asked to identify the direction of the grooves relative to the long axis of the lip
The participants arm is placed in a cast and the index finger is immobilized The same test done on the lip is repeated on the distal part of the index finger
Each part of the test lasts about 20 minutes and the entire experiment takes about 2 hours
Normal volunteers will be recruited for this study Candidates will be screened with physical and neurological examinations Amputee volunteers will be studied at the amputee clinic at the University of Tubingen Germany
Participants will sit comfortably in a chair wearing a blindfold during the following experiments
Plastic domes with grooves are placed on parts of the lower lip on either side for a few seconds The volunteer is then asked to identify the direction of the grooves relative to the long axis of the lip
The participants arm is placed in a cast and the index finger is immobilized The same test done on the lip is repeated on the distal part of the index finger
Each part of the test lasts about 20 minutes and the entire experiment takes about 2 hours
Detailed Description:
Upper limb amputation leads to expansion of the cortical representation of the lip into the adjacent deafferented hand representation It is conceivable that this enlargement of the lip representation may translate into a behavioral gain The purpose of this protocol is to test the hypothesis that upper limb amputation in humans results in higher tactile spatial acuity at the lip This would represent the first demonstration of chronic deafferentation-induced behavioral gains within the somatosensory system
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 02-N-0067 | None | None | None |