Ignite Creation Date:
2024-05-05 @ 9:20 PM
Last Modification Date:
2024-10-26 @ 10:03 AM
Study NCT ID:
NCT00869453
Status:
COMPLETED
Last Update Posted:
2012-07-03
First Post:
2009-03-25
Brief Title:
Gut Hormone Secretion and Macronutrients
Sponsor:
University of Lausanne
Organization:
University of Lausanne
Study Overview
Official Title:
Gut Hormone Secretion Pattern in Response to Different Macronutrients in Healthy Volunteers
Status:
COMPLETED
Status Verified Date:
2012-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The role of gut hormone GLP-1 GIP PYY in glucose homeostasis has been widely demonstrated Furthermore modifications in their pattern of secretion seem to be involved in the improvement of glucose control in obese patients after bariatric surgery
The purpose of this study is to assess the respective role of carbohydrate fat and protein from a complete meal in gut hormones secretion
The purpose of this study is to assess the respective role of carbohydrate fat and protein from a complete meal in gut hormones secretion
Detailed Description:
The study is designed to asses the role of each individual macronutrient of a compete meal in gut hormones secretion in healthy volunteers
8 healthy young male subjects will be studied on 5 different occasions To asses the role of each macronutient the subjects will recieve one of the following test meal a complete sandwich the proteic part of this complete meal the glucidic part and the lipidic part The fifth test will be a fasting test
To assess the entero-insular axis a 55 hours hyperglycaemic clamp will be performed
8 healthy young male subjects will be studied on 5 different occasions To asses the role of each macronutient the subjects will recieve one of the following test meal a complete sandwich the proteic part of this complete meal the glucidic part and the lipidic part The fifth test will be a fasting test
To assess the entero-insular axis a 55 hours hyperglycaemic clamp will be performed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None