Ignite Creation Date:
2024-05-05 @ 9:18 PM
Last Modification Date:
2024-10-26 @ 10:02 AM
Study NCT ID:
NCT00857610
Status:
COMPLETED
Last Update Posted:
2020-03-13
First Post:
2009-03-05
Brief Title:
Retinol-induced Dermatitis in Aged Skin
Sponsor:
University of Michigan
Organization:
University of Michigan
Study Overview
Official Title:
Molecular Analyses of Retinoid-induced Dermatitis in AgedPhotoaged Human Skin
Status:
COMPLETED
Status Verified Date:
2020-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Topical therapy with retinoids is the only proven medical therapy for agedphotoaged human skin However topical therapy with retinoids often result in unwanted cutaneous dermatitis including erythema and scaling The reseachers intend to investigate the dose frequency of use and time dependence of topical retinol-induced dermatitis The researchers intend to evaluate retinoid-induced dermatitis biochemically including retinol regulation of retinoid responsive genes that control retinoid metabolism and serve as markers for retinoid bioactivity The researchers will also investigate the role of EGF receptor pathway in retinoid-induced dermatitis
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None