Ignite Creation Date:
2024-05-05 @ 9:15 PM
Last Modification Date:
2024-10-26 @ 10:01 AM
Study NCT ID:
NCT00843453
Status:
COMPLETED
Last Update Posted:
2009-07-23
First Post:
2009-02-12
Brief Title:
Long-term Use of Proton Pump Inhibitors May Cause Vitamin B12 Deficiency in the Institutionalized Elderly
Sponsor:
University of Delaware
Organization:
University of Delaware
Study Overview
Official Title:
Long-term Use of Proton Pump Inhibitors May Cause Vitamin B12 Deficiency in the Institutionalized Elderly
Status:
COMPLETED
Status Verified Date:
2009-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study was designed to determine whether elderly residents of long term care facilitated who had been taking proton pump inhibitors PPI for more than 12 months were more likely to have vitamin B12 deficiency than residents not taking PPI and whether cyanocobalamin nasal spray improved these subjects vitamin B12 status
Detailed Description:
Subjects had serum creatinine 18 mgdL no diagnosis of severe megaloblastic or pernicious anemia and had not been taking vitamin B12 supplements At baseline serum vitamin B12 and methylmalonic acid MMA concentrations of 34 subjects from the PPI group were compared with those of the non-PPI group The PPI group n13 was treated with cyanocobalamin nasal spray for eight weeks and post-treatment vitamin B12 and MMA concentrations were compared with baseline concentrations
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None