Ignite Creation Date:
2025-12-24 @ 1:29 PM
Ignite Modification Date:
2025-12-28 @ 7:24 AM
Study NCT ID:
NCT01414595
Status:
COMPLETED
Last Update Posted:
2017-06-27
First Post:
2011-08-10
Is Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer
Sponsor:
Alliance for Clinical Trials in Oncology
Organization:
Study Overview
Official Title:
Molecular Characterization of Lung Cancer: A Collaboration With the Cancer Genome Atlas Project (TGCA)
Status:
COMPLETED
Status Verified Date:
2017-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
PURPOSE: This research trial studies tissue samples from patients with non-small cell lung cancer.
PURPOSE: This research trial studies tissue samples from patients with non-small cell lung cancer.
Detailed Description:
OBJECTIVES:
* To identify and characterize single nucleotide variations (SNVs) in non-small cell lung cancer (NSCLC) specimens.
* To identify and characterize structural variations in the genomes of NSCLC specimens.
* To identify and characterize other genomic alterations including, but not limited to, expression profiling and methylation.
OUTLINE: DNA and RNA extracted from archived specimens are analyzed for single nucleotide variations, structural variations in the genomes, and other genomic alterations including, but not limited to, gene expression profiling and methylation. Clinical data related to disease, treatment, and recurrence from each patient sample is also collected.
* To identify and characterize single nucleotide variations (SNVs) in non-small cell lung cancer (NSCLC) specimens.
* To identify and characterize structural variations in the genomes of NSCLC specimens.
* To identify and characterize other genomic alterations including, but not limited to, expression profiling and methylation.
OUTLINE: DNA and RNA extracted from archived specimens are analyzed for single nucleotide variations, structural variations in the genomes, and other genomic alterations including, but not limited to, gene expression profiling and methylation. Clinical data related to disease, treatment, and recurrence from each patient sample is also collected.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: