Ignite Creation Date:
2024-05-05 @ 11:24 AM
Last Modification Date:
2024-10-26 @ 9:07 AM
Study NCT ID:
NCT00029653
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
2002-01-16
Brief Title:
Effect of Transcranial Magnetic Stimulation on Free Will
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
The Effect of Transcranial Magnetic Stimulation on Free Will
Status:
COMPLETED
Status Verified Date:
2002-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will use transcranial magnetic stimulation TMS to investigate how the brain controls movement by sending messages to the spinal cord and muscles
Healthy normal volunteers 21 years of age or older may participate in this study
They must have no medical neurological or psychiatric illnesses nor have been taking medications that affect nervous system function
Participants will undergo transcranial magnetic stimulation For this procedure an insulated wire coil is placed on the scalp or skin A brief electrical current is passed through the coil creating a magnetic pulse that stimulates the brain If the coil is placed over a nerve or area of the brain that controls muscles it may cause a muscle twitch possibly strong enough to move the limb In other cases the subject may have a feeling of movement or feel a tingling sensation in a limb Stimulation over the muscles on the side of the head may cause some discomfort in that area or twitching of the jaw
During the stimulation the subject may be asked to tense certain muscles slightly or perform other simple actions The electrical activity of the muscles activated by the stimulation will be recorded using metal electrodes taped to the skin over the muscle In most cases the study takes less than 3 hours
Healthy normal volunteers 21 years of age or older may participate in this study
They must have no medical neurological or psychiatric illnesses nor have been taking medications that affect nervous system function
Participants will undergo transcranial magnetic stimulation For this procedure an insulated wire coil is placed on the scalp or skin A brief electrical current is passed through the coil creating a magnetic pulse that stimulates the brain If the coil is placed over a nerve or area of the brain that controls muscles it may cause a muscle twitch possibly strong enough to move the limb In other cases the subject may have a feeling of movement or feel a tingling sensation in a limb Stimulation over the muscles on the side of the head may cause some discomfort in that area or twitching of the jaw
During the stimulation the subject may be asked to tense certain muscles slightly or perform other simple actions The electrical activity of the muscles activated by the stimulation will be recorded using metal electrodes taped to the skin over the muscle In most cases the study takes less than 3 hours
Detailed Description:
The purpose of this study is to investigate the influence of transcranial magnetic stimulation TMS on free will to select movement There have been debates that most of human voluntary movements are reflexive rather than volitional in nature although most people feel that their movements are freely chosen This issue is illuminated by previous TMS studies showing external bias of freely chosen movements by TMS Recently we tried to confirm these observations using a more reliable method with subthreshold TMS but failed Thus in this study we are planning to use suprathreshold TMS to test whether this type of stimulation on different motor areas influences free selection of movements or not
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 02-N-0101 | None | None | None |