Ignite Creation Date:
2024-05-05 @ 11:24 AM
Last Modification Date:
2024-10-26 @ 9:06 AM
Study NCT ID:
NCT00020891
Status:
COMPLETED
Last Update Posted:
2013-01-18
First Post:
2001-07-11
Brief Title:
CT Scans in Guiding the Treatment of Patients With Prostate Cancer Who Are Undergoing Radiation Therapy
Sponsor:
Memorial Sloan Kettering Cancer Center
Organization:
Memorial Sloan Kettering Cancer Center
Study Overview
Official Title:
The Use Of Multiple CT Scans To Reduce Target Positioning Errors In Patients Undergoing External Beam Radiotherapy Treatment For Prostate Cancer
Status:
COMPLETED
Status Verified Date:
2013-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
RATIONALE Radiation therapy uses high-energy x-rays to damage tumor cells Multiple CT scans may improve the accuracy of radiation therapy for prostate cancer
PURPOSE Phase I trial to study the effectiveness of multiple CT scans in guiding the treatment of patients who have prostate cancer and are undergoing radiation therapy
PURPOSE Phase I trial to study the effectiveness of multiple CT scans in guiding the treatment of patients who have prostate cancer and are undergoing radiation therapy
Detailed Description:
OBJECTIVES
Compare the accuracy of radiotherapy delivery using multiple CT scans to guide patient positioning vs the standard portal image guided procedure in patients with prostate cancer undergoing external beam radiotherapy
Determine the reduction in the proportion of patients with large target positioning errors using the CT-guided procedure
Determine organ motion and setup errors over the course of radiotherapy in order to develop efficient clinical intervention strategies in these patients
OUTLINE Patients undergo radiotherapy over 9 weeks Patients undergo a CT scan immediately prior to receiving radiotherapy on treatment days 3-8 and then weekly thereafter On 3 different days patients also undergo CT scan immediately after radiotherapy If the CT scans indicate a correction that exceeds the action level currently in effect then beginning with the next treatment the patients position with respect to the radiation field is adjusted
PROJECTED ACCRUAL A total of 25 patients will be accrued for this study within 2 years
Compare the accuracy of radiotherapy delivery using multiple CT scans to guide patient positioning vs the standard portal image guided procedure in patients with prostate cancer undergoing external beam radiotherapy
Determine the reduction in the proportion of patients with large target positioning errors using the CT-guided procedure
Determine organ motion and setup errors over the course of radiotherapy in order to develop efficient clinical intervention strategies in these patients
OUTLINE Patients undergo radiotherapy over 9 weeks Patients undergo a CT scan immediately prior to receiving radiotherapy on treatment days 3-8 and then weekly thereafter On 3 different days patients also undergo CT scan immediately after radiotherapy If the CT scans indicate a correction that exceeds the action level currently in effect then beginning with the next treatment the patients position with respect to the radiation field is adjusted
PROJECTED ACCRUAL A total of 25 patients will be accrued for this study within 2 years
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| P30CA008748 | NIH | None | None |
| MSKCC-01022 | None | None | None |
| NCI-G01-1968 | US NIH GrantContract | None | httpsreporternihgovquickSearchP30CA008748 |