Ignite Creation Date:
2024-05-05 @ 9:08 PM
Last Modification Date:
2024-10-26 @ 10:00 AM
Study NCT ID:
NCT00829699
Status:
COMPLETED
Last Update Posted:
2019-09-12
First Post:
2009-01-23
Brief Title:
Metabolic Causes of Thrombosis in Type 2 Diabetes Mellitus
Sponsor:
University of Maryland Baltimore
Organization:
University of Maryland Baltimore
Study Overview
Official Title:
Metabolic Causes of Thrombosis in Type 2 Diabetes Mellitus Question 3
Status:
COMPLETED
Status Verified Date:
2019-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to learn more about why patients with diabetes have increased heart attacks strokes and other illnesses due to blood clots causing blockage of a blood vessel The proposed protocol will study the separate and combined effects of high glucose and high fats on certain cardiovascular responses in Type 2 DM
Detailed Description:
Currently 75-80 of diabetes mellitus DM patients die due to thrombotic causes Data from the Centers for Disease Control and Prevention released in 2000 indicated that mortality due to coronary artery disease is decreasing except in individuals with diabetes Clearly the disordered metabolism which includes abnormal metabolism of fats resulting in higher triglyceride and free fatty acid blood levels occurring in diabetes predisposes these individuals to increased thrombotic events Unless the underlying mechanisms responsible for these events can be identified there will be an unprecedented number of diabetic patients suffering thrombotic episodes in the next 10 years
The specific aims of this study are to determine the effects of elevated free fatty acids and hyperglycemia high glucoseon endothelial function and thrombolytic balance in patients with type 2 diabetes and to determine the effects of increased insulin in this setting
The specific aims of this study are to determine the effects of elevated free fatty acids and hyperglycemia high glucoseon endothelial function and thrombolytic balance in patients with type 2 diabetes and to determine the effects of increased insulin in this setting
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| RFAHL04016 | None | None | None |