Ignite Creation Date:
2024-05-05 @ 9:08 PM
Last Modification Date:
2024-10-26 @ 9:59 AM
Study NCT ID:
NCT00818714
Status:
WITHDRAWN
Last Update Posted:
2020-03-18
First Post:
2009-01-07
Brief Title:
Stereotactic Body Radiation Therapy SBRT as a Boost After Definitive Concurrent Chemoradiation ChemoRT for Non-Small Cell Lung Cancer NSCLC GCC 0516
Sponsor:
University of Maryland Baltimore
Organization:
University of Maryland Baltimore
Study Overview
Official Title:
0516 GCC Stereotactic Body Radiation Therapy As A Boost After Definitive Treatment With Concurrent Chemoradiation In Patients With Non-Small Cell Lung Cancer
Status:
WITHDRAWN
Status Verified Date:
2020-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
There was no patient accrual nor study activity due to inability to fund PFTs
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
SBRT to deliver a boost dose to residual primary tumor after definitive doses of standard EBRT have been delivered concurrently with chemotherapy
Serum levels of TGF-Beta1 and correlation with SBRT toxicity
Serum levels of TGF-Beta1 and correlation with SBRT toxicity
Detailed Description:
This protocol is designed to use stereotactic body radiation therapy SBRT to deliver a boost dose to residual primary tumor after definitive doses of standard external beam radiation have been delivered concurrently with chemotherapy It is designed to determine the toxicity profileside effects in the context of dose escalation of stereotactic body radiation therapy SBRT after definitive therapy with concurrent chemoradiation and to define the maximum tolerated dose
Serum levels of TGF-Beta1 have been demonstrated to correlate with the incidence of the radiation toxicity pneumonitis in patients treated with standard external beam radiation This study will serially follow TGF-Beta1 levels in patients to see if the same correlation exists with SBRT toxicity
Serum levels of TGF-Beta1 have been demonstrated to correlate with the incidence of the radiation toxicity pneumonitis in patients treated with standard external beam radiation This study will serially follow TGF-Beta1 levels in patients to see if the same correlation exists with SBRT toxicity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| GCC 0516 | None | None | None |