Ignite Creation Date:
2024-05-05 @ 9:02 PM
Last Modification Date:
2024-10-26 @ 9:58 AM
Study NCT ID:
NCT00800852
Status:
COMPLETED
Last Update Posted:
2008-12-02
First Post:
2008-11-30
Brief Title:
Increased Expression of Adiponectin Receptor 2 in the Mononuclear Cells in Children With Prader-Willi Syndrome
Sponsor:
Samsung Medical Center
Organization:
Samsung Medical Center
Study Overview
Official Title:
Increased Expression of Adiponectin Receptor 2 in the Mononuclear Cells in Children With Prader-Willi Syndrome
Status:
COMPLETED
Status Verified Date:
2008-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The inflammatory process is involved in the pathogenesis of obesity Prader-Willi syndrome PWS is a genetic model of syndromic obesity Adiponectin is an adipokine with potent anti-inflammatory properties and its effect is mediated through adiponectin receptors 1 adipoR1 and 2 adipoR2
Objective of this study is to compare the expression of adipoR1 adipoR2 and adiponectin in peripheral blood mononuclear cells PBMCs in PWS children and obese control and to correlate receptor expression with insulin sensitivity and obesity-related parameters
Objective of this study is to compare the expression of adipoR1 adipoR2 and adiponectin in peripheral blood mononuclear cells PBMCs in PWS children and obese control and to correlate receptor expression with insulin sensitivity and obesity-related parameters
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None