Ignite Creation Date:
2024-05-05 @ 11:23 AM
Last Modification Date:
2024-10-26 @ 9:06 AM
Study NCT ID:
NCT00010530
Status:
COMPLETED
Last Update Posted:
2009-12-07
First Post:
2001-02-02
Brief Title:
Basic Mechanisms of Meditation and Cardiovascular Disease in Older Blacks
Sponsor:
National Center for Complementary and Integrative Health NCCIH
Organization:
National Center for Complementary and Integrative Health NCCIH
Study Overview
Official Title:
Basic Mechanisms of Meditation and Cardiovascular Disease in Older Blacks
Status:
COMPLETED
Status Verified Date:
2009-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to evaluate the effects of meditation on older African Americans with documented cardiovascular disease CVD
Detailed Description:
Cardiovascular disease CVD is the leading cause of death and disability in older African Americans and accounts for 40 of the disproportionate risk for mortality observed in African Americans compared to white Americans The majority of CVD patients experience acute cardiac events many sudden and unexpected despite conventional treatment of their disease and associated traditional risk factors The pathophysiologic basis of these cardiac events is not fully established but substantial evidence indicates that psychosocial stress and the sympathetic nervous system have adverse effects on both vasomotor function and long-term autonomic balance Recent advances in the understanding of the pathophysiology of acute cardiac events-specifically the roles that arterial vasomotor dysfunction and sympathetic nervous system imbalance play in the pathophysiology of such acute events-provide a platform for a new mechanistic investigation of the interplay of psychosocial and environmental stress and CVD Preliminary evidence demonstrating elevated peripheral vasoconstriction due to stress-mediated sympathetic nervous system response in African Americans further suggests that these mechanisms are particularly relevant in this group
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| P50AT000082-02 | NIH | None | httpsreporternihgovquickSearchP50AT000082-02 |
| P50AT000082-01 | NIH | None | None |