Ignite Creation Date:
2024-05-05 @ 7:50 PM
Last Modification Date:
2024-10-26 @ 9:55 AM
Study NCT ID:
NCT00758654
Status:
COMPLETED
Last Update Posted:
2012-03-30
First Post:
2008-09-23
Brief Title:
Strain-Encoded Cardiac Magnetic Resonance Imaging for Dobutamine Stress Testing
Sponsor:
Heidelberg University
Organization:
Heidelberg University
Study Overview
Official Title:
Strain-Encoded Cardiac Magnetic Resonance Imaging as an Adjunct for Dobutamine Stress Testing
Status:
COMPLETED
Status Verified Date:
2012-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to compare the diagnostic value of SENC to that provided by conventional wall motion analysis for the detection of inducible ischemia during DS-MRIHigh-dose dobutamine stress magnetic resonance imaging DS-MRI is safe and feasible for the diagnosis of coronary artery disease CAD in humans However the assessment of cine scans relies on the visual interpretation of regional wall motion which is subjective Recently Strain-Encoded MRI SENC has been proposed for the direct color-coded visualization of myocardial strain
Detailed Description:
The assessment of inducible regional wall motion abnormalities during high-dose dobutamine stress magnetic resonance imaging DS-MRI is an established clinical method with high diagnostic and prognostic value for the evaluation of patients with coronary artery disease CAD However the assessment of cine images relies on the visual interpretation of regional wall motion which is subjective and objective approaches for the detection of inducible ischemia with DS-MRI are still lacking
In our study Strain-Encoded-MRI SENC is used for the objective color-coded evaluation of regional myocardial strain during DS-MRI in patients with intermediate to high pretest probability for CAD We anticipated that this technique would exhibit enhanced sensitivity for the detection of anatomically significant CAD compared to conventional wall motion reading with invasive coronary angiography used as the standard reference
In our study Strain-Encoded-MRI SENC is used for the objective color-coded evaluation of regional myocardial strain during DS-MRI in patients with intermediate to high pretest probability for CAD We anticipated that this technique would exhibit enhanced sensitivity for the detection of anatomically significant CAD compared to conventional wall motion reading with invasive coronary angiography used as the standard reference
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None