Ignite Creation Date:
2024-05-05 @ 7:47 PM
Last Modification Date:
2024-10-26 @ 9:53 AM
Study NCT ID:
NCT00731601
Status:
COMPLETED
Last Update Posted:
2009-04-07
First Post:
2008-08-07
Brief Title:
Intravenous Proton Pump Inhibitor for Peptic Ulcer Bleeding
Sponsor:
Lotung Poh-Ai Hospital
Organization:
Lotung Poh-Ai Hospital
Study Overview
Official Title:
Phase 4 Study of Intravenous Proton Pump Inhibitor in Patients With Peptic Ulcer Bleeding After Successful Endoscopic Therapy- a Prospective Randomized Comparative Trial
Status:
COMPLETED
Status Verified Date:
2009-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PPI
Brief Summary:
A large dose of PPI is effective in preventing peptic ulcer rebleeding The investigators hypothesize that 40 mgq6h pantoloc is equivalent to 8mgh pantoloc in preventing rebleeding
Detailed Description:
A bleeding peptic ulcer remains a serious medical problem with significant morbidity and mortality Endoscopic therapy significantly reduces further bleeding surgery and mortality in patients with bleeding peptic ulcers and is now recommended as the first hemostatic modality for these patients
In the past few years adjuvant use of a high-dose proton pump inhibitor PPI after endoscopic therapy has been endorsed in some studies two consensus statements and two meta-analysis In our previous experience we used omeprazole 160 mg day infusion instead of 8 mgh in these patients and obtained a good result
The objectives of this study are to assess the outcomes of two different regimens of high dose of intravenous pantoprazole after endoscopic therapy in patients with peptic ulcer bleeding
In the past few years adjuvant use of a high-dose proton pump inhibitor PPI after endoscopic therapy has been endorsed in some studies two consensus statements and two meta-analysis In our previous experience we used omeprazole 160 mg day infusion instead of 8 mgh in these patients and obtained a good result
The objectives of this study are to assess the outcomes of two different regimens of high dose of intravenous pantoprazole after endoscopic therapy in patients with peptic ulcer bleeding
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None