Ignite Creation Date:
2024-05-05 @ 11:23 AM
Last Modification Date:
2024-10-26 @ 9:06 AM
Study NCT ID:
NCT00015613
Status:
COMPLETED
Last Update Posted:
2005-11-03
First Post:
2001-04-23
Brief Title:
Farm Work Preterm Low Birthweight Among Hispanic Women
Sponsor:
National Institute of Environmental Health Sciences NIEHS
Organization:
National Institute of Environmental Health Sciences NIEHS
Study Overview
Official Title:
Study of Hispanic Acculturation Reproduction and the Environment SHARE
Status:
COMPLETED
Status Verified Date:
2002-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The most persistent and intractable cause of infant and child mortality and morbidity in the US remains preterm and low birthweight deliveries Pregnant women in the United States experience the highest incidence of these complications among developed countries Even more disturbing is the observation that immigrant Hispanic women experience worsening birth outcomes the longer they live here despite increasing access to prenatal care improved socio-economic status and better education The purpose of this study is to identify the potential acculturation-related risk factors for preterm and low birthweight PTLBW delivery among Hispanic women of varying lengths of US residency It is hypothesized that changes in factors associated with acculturation such as poor nutritional intake job stress and occupational exposures to pesticides or other hazards and certain types of genital infections can best explain the worsening of pregnancy outcomes among Hispanic immigrant women
Detailed Description:
The most persistent and intractable cause of infant and child mortality and morbidity in the US remains preterm and low birthweight deliveries Pregnant women in the US experience the highest incidence of these complications among developed countries Despite many efforts at increasing prenatal care rates of preterm delivery have not substantially changed in the last decade Even more disturbing is the observation that immigrant Hispanic women experience worsening birth outcomes the longer they live in the US despite increasing access to prenatal care improved socio-economic status and better education Within five years after moving to the US the odds ratio for preterm low birth weight delivery increases by 19 from 4 to 7
As migrant women become acculturated to the US they must be exposed to factors that adversely affect pregnancy outcomes But the known risk factors such as poverty lack of education smoking substance abuse inadequate pregnancy weight gain low pre-pregnancy weight high altitude chronic diseases primipara and high parity explain only a small percentage of this change in incidence
The prospective study will enroll a cohort of approximately 1500 pregnant Hispanic women attending prenatal care services through an OBGYN group at the San Joaquin General Hospital in Stockton CA The majority of Hispanic women 67 receiving prenatal care through this group are Mexican immigrants of varying lengths of US residency and up to 26 of them are involved in farm labor andor other types of manual labor Eighteen percent are US-born Mexican women A study of this unique population of Hispanic women of varying lengths of US residency and factors related to occupational risks acculturation and preterm low birth weight deliveries will provide an excellent opportunity to examine the factors of acculturation-based causes of preterm low birthweight PTLBW
The investigators hypothesize that job stress and occupational exposures related to farm work can best explain the worsening of pregnancy outcomes among Hispanic women However in order to ensure an understanding of the mechanism of this increased rate of preterm low birthweight within this population this study will also examine other risk factors that could possibly be associated with acculturation and preterm low birthweight Such factors include changes in nutrition intake and certain types of genital infections such as Bacterial Vaginosis Gonorrhea and Chlamydia
The knowledge that emerges will have direct application for designing improved programs for the prevention of preterm low birthweight deliveries among Hispanic women Just as important it will provide insight into the underlying causes of the scandalously high rates throughout all US populations
As migrant women become acculturated to the US they must be exposed to factors that adversely affect pregnancy outcomes But the known risk factors such as poverty lack of education smoking substance abuse inadequate pregnancy weight gain low pre-pregnancy weight high altitude chronic diseases primipara and high parity explain only a small percentage of this change in incidence
The prospective study will enroll a cohort of approximately 1500 pregnant Hispanic women attending prenatal care services through an OBGYN group at the San Joaquin General Hospital in Stockton CA The majority of Hispanic women 67 receiving prenatal care through this group are Mexican immigrants of varying lengths of US residency and up to 26 of them are involved in farm labor andor other types of manual labor Eighteen percent are US-born Mexican women A study of this unique population of Hispanic women of varying lengths of US residency and factors related to occupational risks acculturation and preterm low birth weight deliveries will provide an excellent opportunity to examine the factors of acculturation-based causes of preterm low birthweight PTLBW
The investigators hypothesize that job stress and occupational exposures related to farm work can best explain the worsening of pregnancy outcomes among Hispanic women However in order to ensure an understanding of the mechanism of this increased rate of preterm low birthweight within this population this study will also examine other risk factors that could possibly be associated with acculturation and preterm low birthweight Such factors include changes in nutrition intake and certain types of genital infections such as Bacterial Vaginosis Gonorrhea and Chlamydia
The knowledge that emerges will have direct application for designing improved programs for the prevention of preterm low birthweight deliveries among Hispanic women Just as important it will provide insight into the underlying causes of the scandalously high rates throughout all US populations
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None