Ignite Creation Date:
2024-05-05 @ 7:38 PM
Last Modification Date:
2024-10-26 @ 9:51 AM
Study NCT ID:
NCT00705965
Status:
COMPLETED
Last Update Posted:
2016-08-30
First Post:
2008-06-25
Brief Title:
Effects of a Psychotherapy Intervention in Depressed Patients With Coronary Artery Disease
Sponsor:
University of Göttingen
Organization:
University of Göttingen
Study Overview
Official Title:
A Stepwise Psychotherapy Intervention for Reducing Risk in Coronary Artery Disease - a Randomised Controlled Trial SPIRR-CAD
Status:
COMPLETED
Status Verified Date:
2016-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SPIRR-CAD
Brief Summary:
In patients with coronary artery disease CAD depressive symptoms are frequent and highly relevant for quality of life health behaviour health care costs and prognosis The aim of the current study is to evaluate the effects of a psychotherapy intervention on symptoms of depression in patients with CAD Therefore depressed patients diagnosed with CAD will be randomised into a controlled intervention trial comparing a stepwise psychotherapy intervention with usual cardiological care The manualized psychotherapy intervention starts with three individual sessions offered on a weekly basis Afterwards symptoms of depression will be re-evaluated and in case of persisting symptoms patients receive an additional 25 sessions of psychodynamic group psychotherapy over a total period of one year The psychodynamic approach was chosen in order to specifically take into account personality traits such as negative affectivity and social inhibition the components of the Type D personality which may explain why recent cognitive behavioural psychotherapy CBT trials produced only small effects in depressed CAD patients The investigators expect that the intervention will reduce depressive symptoms as well as the prevalence of depressive disorders It will also improve both behaviourally and physiologically mediated cardiovascular risk indicators promote better quality of life and reduce healthcare costs Subgroup analyses will be performed in order to identify gender-specific treatment effects effects on immunological stress reactivity and genetic predictors of treatment success
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None